Lipman B, Neu H C
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York.
Med Clin North Am. 1988 May;72(3):567-79. doi: 10.1016/s0025-7125(16)30759-3.
Imipenem is a new carbapenem antibiotic that has an extremely broad spectrum of antibacterial activity. It has been used to treat a variety of serious infections and an increasing volume of literature documents its value in infections due to multiresistant bacteria. This article reviews the antibacterial activity, pharmacology, and clinical uses of imipenem.
亚胺培南是一种新型碳青霉烯类抗生素,具有极广的抗菌谱。它已被用于治疗各种严重感染,越来越多的文献证明了其在多重耐药菌感染中的价值。本文综述了亚胺培南的抗菌活性、药理学及临床应用。