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中美洲萨尔瓦多一个疟疾高发沿海地区的疟疾实地研究

Malaria field studies in a high-incidence coastal area of El Salvador, C.A.

作者信息

Mason J, Hobbs J

出版信息

Bull Pan Am Health Organ. 1977;11(1):17-30.

PMID:328096
Abstract

A three-year investigation was made of the incidence patterns and characteristics of malaria in a small high-incidence coastal area of El Salvador with a resident population of about 6,000 persons and a migrant population of 3,000 to 4,000 others. It found a significant increase in the incidence of Plasmodium falciparum cases during the three-year period, combined with relative stability in the annual number of Plasmodium vivax cases. A close correlation was observed between the seasonal occurence of P. falciparum cases in 1973 and vector densities, and between vector densities and aerial application of agricultural insecticides. Cases of P. vivax appeared about twice as common in the 5 to 14 year age group as in older or younger groups, and cases of P. falciparum seemed only about one-third as frequent in the 0 to 4 year group as in older groups. The attack rate in 1973 was somewhat higher in males than in females. There appeared to be a decrease in parasite densities with age, as well as a direct correlation between parasite densities and the degree of disability (symptoms and "in bed" time) reported by patients.

摘要

在萨尔瓦多一个沿海小高发区,对约6000名常住人口和3000至4000名流动人口进行了为期三年的疟疾发病模式及特征调查。结果发现,在这三年期间,恶性疟原虫病例的发病率显著上升,而间日疟原虫病例的年发病数相对稳定。观察到1973年恶性疟原虫病例的季节性发生与媒介密度之间、媒介密度与农业杀虫剂空中喷洒之间存在密切关联。间日疟原虫病例在5至14岁年龄组的出现频率约为其他年龄组的两倍,而恶性疟原虫病例在0至4岁组的出现频率似乎仅为其他年龄组的三分之一左右。1973年男性的发病率略高于女性。随着年龄增长,寄生虫密度似乎有所下降,并且寄生虫密度与患者报告的残疾程度(症状和“卧床”时间)之间存在直接关联。

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