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SOS比色试验的评估。

Evaluation of the SOS chromotest.

作者信息

von der Hude W, Behm C, Gürtler R, Basler A

机构信息

Max von Pettenkofer-Institut des Bundesgesundheitsamtes, Berlin, F.R.G.

出版信息

Mutat Res. 1988 Apr;203(2):81-94. doi: 10.1016/0165-1161(88)90023-4.

DOI:10.1016/0165-1161(88)90023-4
PMID:3280989
Abstract

In the present investigation, the SOS chromotest with E. coli PQ37 was evaluated. The potential to identify different kinds of bacterial mutagens was examined. 124 chemicals of different chemical classes were tested. Their responses in the SOS chromotests were compared to reported test results obtained with the Ames test.

摘要

在本研究中,对采用大肠杆菌PQ37的SOS显色试验进行了评估。研究了识别不同种类细菌诱变剂的潜力。测试了124种不同化学类别的化学物质。将它们在SOS显色试验中的反应与通过艾姆斯试验获得的报告测试结果进行了比较。

相似文献

1
Evaluation of the SOS chromotest.SOS比色试验的评估。
Mutat Res. 1988 Apr;203(2):81-94. doi: 10.1016/0165-1161(88)90023-4.
2
Further studies on the detection of mutagenic and genotoxic activity in human faeces: aerobic and anaerobic fluctuation tests with S. typhimurium and E. coli, and the SOS Chromotest.人体粪便中诱变和基因毒性活性检测的进一步研究:鼠伤寒沙门氏菌和大肠杆菌的需氧及厌氧波动试验,以及SOS色变试验
Mutagenesis. 1986 Jan;1(1):49-64. doi: 10.1093/mutage/1.1.49.
3
The SOS Chromotest, a colorimetric bacterial assay for genotoxins: validation study with 83 compounds.SOS比色法检测基因毒素:83种化合物的验证研究
Mutat Res. 1985 Jun;147(3):79-95. doi: 10.1016/0165-1161(85)90021-4.
4
SOS induction of selected naturally occurring substances in Escherichia coli (SOS chromotest).大肠杆菌中选定天然物质的SOS诱导(SOS色变试验)
Mutat Res. 1999 Sep 15;445(1):81-91. doi: 10.1016/s1383-5718(99)00141-2.
5
Epoxides: comparison of the induction of SOS repair in Escherichia coli PQ37 and the bacterial mutagenicity in the Ames test.
Mutat Res. 1990 Aug;231(2):205-18. doi: 10.1016/0027-5107(90)90027-2.
6
[Characteristics of the mutagenic and toxic effects of ethylene imine and its oligomers. Comparative study in the automated SOS-chromotest system and in standard bacterial test systems].[乙撑亚胺及其低聚物的诱变和毒性作用特征。在自动SOS-显色试验系统和标准细菌试验系统中的比较研究]
Genetika. 1988 Apr;24(4):763-5.
7
Evaluation of the SOS chromotest for detection of genotoxic drugs.
Acta Microbiol Pol. 1993;42(2):205-8.
8
Use of the SOS chromotest, the Ames-fluctuation test and the newt micronucleus test to study the genotoxicity of four trihalomethanes.使用SOS比色试验、艾姆斯波动试验和蝾螈微核试验来研究四种三卤甲烷的遗传毒性。
Mutagenesis. 1995 Jul;10(4):333-41. doi: 10.1093/mutage/10.4.333.
9
A comparative study of mutagenic and SOS-inducing activity of biphenyls, phenanthrenequinones and fluorenones.
Mutat Res. 1990 Aug;244(4):321-9. doi: 10.1016/0165-7992(90)90080-4.
10
Induction of SOS repair by monofunctional methanesulphonates in various Escherichia coli strains. Structure-activity relationships in comparison with mutagenicity in Salmonella typhimurium.
Mutagenesis. 1989 May;4(3):179-86. doi: 10.1093/mutage/4.3.179.

引用本文的文献

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Rapid detection of genotoxicity employing an engineered high-sensitivity and tight SOS-response biosensor in MG1655.利用工程化的高灵敏度且紧密的SOS反应生物传感器在MG1655中快速检测遗传毒性。
Synth Syst Biotechnol. 2025 Jun 27;11:117-126. doi: 10.1016/j.synbio.2025.06.011. eCollection 2026 Mar.
2
The influence of organic solvents on estimates of genotoxicity and antigenotoxicity in the SOS chromotest.有机溶剂对 SOS 显色试验中遗传毒性和抗原毒性估算的影响。
Genet Mol Biol. 2012 Apr;35(2):503-14. doi: 10.1590/S1415-47572012000300018. Epub 2012 Jun 23.
3
Bacterial genotoxicity bioreporters.
细菌遗传毒性生物报告器。
Microb Biotechnol. 2010 Jul;3(4):412-27. doi: 10.1111/j.1751-7915.2009.00160.x. Epub 2009 Dec 29.
4
Quantitative assessment of groundwater quality using a biological indicator: some preliminary observations.利用生物指标对地下水水质进行定量评估:一些初步观察结果。
Arch Environ Contam Toxicol. 1994 Feb;26(2):201-7. doi: 10.1007/BF00224805.
5
Induction of the SOS response by hydrogen peroxide in various Escherichia coli mutants with altered protection against oxidative DNA damage.过氧化氢在各种对氧化性DNA损伤防护能力改变的大肠杆菌突变体中诱导SOS反应。
J Bacteriol. 1989 Nov;171(11):6141-7. doi: 10.1128/jb.171.11.6141-6147.1989.