Suppr超能文献

肯尼亚接受人类免疫缺陷病毒辅助性伴侣服务的索引客户及其性伴侣中与人类免疫缺陷病毒护理不良联系相关的因素。

Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya.

机构信息

From the Research and Programs, Kenyatta National Hospital, Nairobi, Kenya.

Department of Epidemiology, University of Washington, Seattle, WA.

出版信息

Sex Transm Dis. 2020 Sep;47(9):610-616. doi: 10.1097/OLQ.0000000000001222.

Abstract

INTRODUCTION

Human immunodeficiency virus (HIV) assisted partner services (aPS) has been recommended as a strategy to increase HIV case finding. We evaluated factors associated with poor linkage to HIV care among newly diagnosed HIV-positive individuals (index clients) and their partners after receiving aPS in Kenya.

METHODS

In a cluster randomized trial conducted between 2013 and 2015, 9 facilities were randomized to immediate aPS (intervention). Linkage to care-defined as HIV clinic registration, and antiretroviral therapy (ART) initiation were self-reported. Antiretroviral therapy was only offered to those with CD4 less than 500 during this period. We estimated linkage to care and ART initiation separately for index clients and their partners using log-binomial generalized estimating equation models with exchangeable correlation structure and robust standard errors.

RESULTS

Overall, 550 index clients and 621 sex partners enrolled, of whom 46% (284 of 621) were HIV-positive. Of the 284, 264 (93%) sex partners returned at 6 weeks: 120 newly diagnosed and 144 whom had known HIV-positive status. Among the 120 newly diagnosed, only 69% (83) linked to care at 6 weeks, whereas among the 18 known HIV-positive sex partners not already in care at baseline, 61% (11) linked. Newly diagnosed HIV-positive sex partners who were younger and single were less likely to link to care (P < 0.05 for all).

CONCLUSION

Only two thirds of newly diagnosed, and known HIV-positive sex partners not in care linked to care after receiving aPS. The HIV aPS programs should optimize HIV care for newly diagnosed HIV-positive sex partners, especially those who are younger and single.

摘要

引言

人类免疫缺陷病毒(HIV)辅助伙伴服务(aPS)已被推荐为增加 HIV 病例发现的策略。我们评估了肯尼亚在接受 aPS 后新诊断出 HIV 阳性个体(索引客户)及其伴侣与 HIV 护理联系不良的相关因素。

方法

在 2013 年至 2015 年期间进行的一项集群随机试验中,9 个设施被随机分配到立即接受 aPS(干预)。联系护理定义为 HIV 诊所登记和开始抗逆转录病毒治疗(ART)。在此期间,仅向 CD4 小于 500 的人提供抗逆转录病毒治疗。我们使用具有可交换相关结构和稳健标准误差的对数二项式广义估计方程模型分别为索引客户和他们的伴侣估计联系护理和开始接受抗逆转录病毒治疗。

结果

总体而言,550 名索引客户和 621 名性伴侣入组,其中 46%(621 名中的 284 名)为 HIV 阳性。在这 284 名中,有 264 名(93%)性伴侣在 6 周时返回:120 名新诊断出患有 HIV 阳性,144 名已知 HIV 阳性。在 120 名新诊断出患有 HIV 阳性的患者中,只有 69%(83 名)在 6 周时联系护理,而在 18 名已知 HIV 阳性但基线时未接受护理的性伴侣中,有 61%(11 名)联系。新诊断出患有 HIV 阳性的年轻和单身性伴侣更不可能联系护理(所有 P < 0.05)。

结论

只有三分之二的新诊断出患有 HIV 阳性且不在护理中的性伴侣和已知 HIV 阳性但不在护理中的性伴侣在接受 aPS 后联系护理。HIV aPS 计划应优化新诊断出 HIV 阳性性伴侣的 HIV 护理,特别是那些年轻和单身的性伴侣。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验