在热带国家泰国进行光贴试验：20 年的经验。
Photopatch testing in a tropical country, Thailand: 20 years' experience.
机构信息
Department of Dermatology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.
出版信息
Photodermatol Photoimmunol Photomed. 2021 Jan;37(1):28-33. doi: 10.1111/phpp.12603. Epub 2020 Sep 10.
BACKGROUND
Photoallergic contact dermatitis is one of the important parts of photodermatoses. The investigation of choice is photopatch testing. However, reports with photopatch test results from Asian countries are scarce. The objective of this study was to determine the prevalence of positive photopatch test reactions and to ascertain the common photoallergens among Thai patients during 1998-2018.
METHODS
We retrospectively reviewed the records of 339 patients who were clinically suspected of having photoallergic contact dermatitis and had undergone photopatch testing.
RESULTS
A total of 44 photoallergic contact reactions in 38 patients (11.2%) were found. The positive photoallergic reactions were mainly found with organic ultraviolet filters and fragrances.
CONCLUSIONS
Organic ultraviolet filter chemicals especially benzophenone-3 and fragrances were found to have a high prevalence of photoallergic contact reactions. Monitoring of the photoallergens employed in photopatch tests should be conducted periodically to provide the best patient care.
背景
光变应性接触性皮炎是光皮肤病的重要组成部分之一。选择的检查是光斑贴试验。然而，来自亚洲国家的光斑贴试验结果报告却很少。本研究的目的是确定泰国患者在 1998 年至 2018 年间光斑贴试验阳性反应的发生率，并确定常见的光变应原。
方法
我们回顾性分析了 339 例临床疑似光变应性接触性皮炎并接受光斑贴试验的患者的记录。
结果
共发现 38 例患者（11.2%）出现 44 种光变应性接触反应。阳性光变应性反应主要与有机紫外线滤光剂和香料有关。
结论
有机紫外线滤光剂化学品，特别是二苯甲酮-3 和香料，被发现具有很高的光变应性接触反应发生率。应定期监测光斑贴试验中使用的光变应原，以提供最佳的患者护理。
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