Dermatology Department, Hospital Clínico de Salamanca, Salamanca, Spain.
Preventive Medicine and Public Health, Universidad de Salamanca, Salamanca, Spain.
Photodermatol Photoimmunol Photomed. 2021 Sep;37(5):449-453. doi: 10.1111/phpp.12680. Epub 2021 May 8.
The diagnosis of photoallergic contact dermatitis (PACD) is confirmed by photopatch testing (PPT). In Spain, the latest recommendation on which allergens to test in PPT dates from 1995.
In the last 4 years, we studied 455 patients with epicutaneous tests and performed PPT on 33 of those patients (7.3%).
The most prevalent allergens in PPT were as follows: non-steroidal anti-inflammatory drugs (NSAIDs) (46%), fragrances (21%), and solar filters (18%).
In our country, the most common photoallergens continue to be NSAIDs (ketoprofen). The increasingly common use of sunscreens has led to a growing involvement of solar filters in PACD, which can be also contained in other cosmetics. In our experience, PACD due to fragrances is nonetheless at least similar in frequency.
The PPT battery must adapt to the prescription, use, and exposure habits of each country. We propose a diagnostic model to guide which allergens to test in PPT, which in our experience should also include fragrances.
光变应性接触性皮炎（PACD）的诊断通过光斑贴试验（PPT）确认。在西班牙，关于 PPT 中应测试哪些过敏原的最新建议可追溯到 1995 年。
在过去的 4 年中，我们对 455 例患者进行了皮内试验，并对其中的 33 例（7.3%）患者进行了 PPT。
PPT 中最常见的过敏原如下：非甾体抗炎药（NSAIDs）（46%）、香料（21%）和防晒剂（18%）。
在我们国家，最常见的光变应原仍然是非甾体抗炎药（酮洛芬）。防晒霜的使用越来越普遍，导致防晒剂在 PACD 中的参与度不断增加，而防晒剂也可能存在于其他化妆品中。根据我们的经验，由于香料引起的 PACD 至少在频率上是相似的。
PPT 电池必须适应每个国家的处方、使用和暴露习惯。我们提出了一个诊断模型来指导 PPT 中应测试哪些过敏原，根据我们的经验，该模型还应包括香料。
