From the Department of Dermatology, Greenlane Clinical Centre, Auckland, New Zealand.
Dermatitis. 2021;32(1):53-56. doi: 10.1097/DER.0000000000000683.
Little is known about the common photoallergens in New Zealand, where ultraviolet exposure is particularly high. Availability of photopatch testing is limited because of it being performed in very few tertiary referral and contact dermatitis clinics.
To review the photopatch testing experience in New Zealand.
A retrospective review of all patients who underwent photopatch testing at a tertiary referral center in Auckland from 2008 to 2019 was performed.
Seventy patients had photopatch testing over the 12-year period. Of the 58 patients tested using the photoallergen series, 6 (10%) patients had a positive photopatch test reaction, of which 4 were to promethazine and 2 were to benzophenone-3. The most common postpatch diagnosis was endogenous dermatitis (54%), followed by allergic contact dermatitis (21%), photoallergic contact dermatitis (9%), and chronic actinic dermatitis (4%).
Both patch and photopatch testing are important investigations in patients with suspected photoallergic contact dermatitis. Promethazine and benzophenone-3 were the most frequent and only photoallergens in our population. Promethazine sensitization was via oral exposure, supporting a mechanism of systematized photoallergy to promethazine.
在紫外线暴露特别高的新西兰，人们对常见的光变应原知之甚少。由于光贴试验只能在极少数的三级转诊和接触性皮炎诊所进行，因此其可用性有限。
回顾新西兰的光贴试验经验。
对 2008 年至 2019 年在奥克兰一家三级转诊中心进行光贴试验的所有患者进行回顾性分析。
在 12 年期间，70 名患者接受了光贴试验。在使用光变应原系列进行测试的 58 名患者中，有 6 名（10%）患者出现阳性光贴试验反应，其中 4 名对异丙嗪，2 名对二苯甲酮-3。最常见的贴后诊断是内源性皮炎（54%），其次是过敏性接触性皮炎（21%）、光变应性接触性皮炎（9%）和慢性光化性皮炎（4%）。
斑贴试验和光贴试验都是疑似光变应性接触性皮炎患者的重要检查。异丙嗪和二苯甲酮-3是我们人群中最常见和唯一的光变应原。异丙嗪致敏是通过口服暴露引起的，支持异丙嗪系统性光变应的机制。
