as a Reservoir of A to in Non-Migratory Seabirds from a Remote Oceanic Island.

Genomic analysis of a methicillin-resistant (MRSA) strain cultured from a non-migratory seabird at Fernando de Noronha Archipelago (Brazilian oceanic islands) was carried out to investigate the potential origin of MRSA genetic determinants in an ecological setting with minimal or absent antimicrobial selective pressure, and minimal interaction with humans and domestic animals. The study determined A gene homology and the phylogenetic relatedness with A described in , which was the major spp. cultured from the birds. Our findings corroborate assumptions that the A gene in MRSA strains clinically relevant for humans and animals originates from ancestors. Coagulase-negative staphylococci seem to be natural reservoirs of methicillin-resistant genes to , even in environments with very low antimicrobial selection pressure.