Hampson D J, Fu Z F, Bettleheim K A, Wilson M W
Department of Veterinary Pathology, Massey University, Palmerston North, New Zealand.
Epidemiol Infect. 1988 Apr;100(2):213-20. doi: 10.1017/s0950268800067340.
In an experimental study on a piggery it was found that haemolytic Escherichia coli of O-serotypes 138 or 139 proliferated in the intestinal tracts of pigs following weaning, with E. coli of the O-138 type also being occasionally recovered from unweaned pigs, and once from a sow. Organisms of the O-138 type produced heat labile enterotoxin and their presence in weaned pigs was associated with the development of severe post-weaning diarrhoea. E. coli of O-139 type produced a vero cell cytotoxin and were associated with a milder diarrhoea in weaned pigs. Under various managemental circumstances the O-138 type E. coli almost invariably proliferated after weaning. The O-139 strain of E. coli did however proliferate rather than the O-138 strain following the movement of weaned pigs to new accommodation, after weaned pigs were returned to their sow and then weaning again 5 days later, and very occasionally in pigs weaned at 5 weeks of age. In all these cases earlier proliferation of the O-138 E. coli had been detected, suggesting that this may be a prerequisite for proliferation of the O-139 strain.
在一项针对养猪场的实验研究中发现，O血清型138或139的溶血性大肠杆菌在断奶后的猪肠道中增殖，O-138型大肠杆菌偶尔也从未断奶的仔猪中分离出来，还曾从一头母猪中分离到。O-138型菌株产生热不稳定肠毒素，其在断奶仔猪中的存在与严重的断奶后腹泻的发生有关。O-139型大肠杆菌产生一种维罗细胞毒素，与断奶仔猪中较轻的腹泻有关。在各种管理条件下，O-138型大肠杆菌在断奶后几乎总是会增殖。然而，在断奶仔猪转移到新猪舍后、断奶仔猪回到母猪身边然后5天后再次断奶时，以及在5周龄断奶的仔猪中极少数情况下，增殖的是O-139型大肠杆菌菌株而非O-138型菌株。在所有这些情况下，之前都检测到O-138大肠杆菌的早期增殖，这表明这可能是O-139菌株增殖的一个先决条件。
