Takahashi N, Chifu S, Matsuo K, Nakao S, Noguchi K, Kohno T, Takahara O
Dept. of Internal Medicine, Japanese Red Cross Nagasaki Atomic Bomb Hospital.
Gan No Rinsho. 1988 Mar;34(3):331-41.
Primary mediastinal seminoma is a rare germ cell tumor that is histologically identical to testicular seminoma. Fifty-one cases have been reported in the Japanese literature. This report concerns a new case of this tumor which showed high levels of a serum alkaline phosphatase (ALP) and a serum angiotensin converting enzyme (ACE). The patient is a 27 year old man whose father underwent an orchiectomy with postoperative radiation therapy for testicular tumor. After radiation and chemotherapy, the patient's chest X-ray showed complete regression of the mass, and his ALP and ACE decreased to normal levels.
原发性纵隔精原细胞瘤是一种罕见的生殖细胞肿瘤，组织学上与睾丸精原细胞瘤相同。日本文献中已报道了51例。本报告涉及该肿瘤的一例新病例，其血清碱性磷酸酶（ALP）和血清血管紧张素转换酶（ACE）水平升高。患者为一名27岁男性，其父亲曾因睾丸肿瘤接受睾丸切除术及术后放疗。放疗和化疗后，患者胸部X线显示肿块完全消退，其ALP和ACE降至正常水平。
