Kakudo K, Hasegawa H, Komatsu N, Nakamura A, Itoh Y, Watanabe K
Department of Pathology, Tokai University School of Medicine, Bouseidai Ishehara, Kanagawa, Japan.
Brain Res. 1988 Feb 2;440(1):153-8. doi: 10.1016/0006-8993(88)91168-7.
The localization of immunoreactive calcitonin gene-related peptide (IR-CGRP) in vagus nerve fibers of the rat was studied with pre-embedding electron immunocytochemistry. IR-CGRP was localized in a small number (approximately 5%) of myelinated fibers and approximately 50% of unmyelinated fibers of the vagus. The immumoreactivity was observed in the dense cored vesicles (75-150 nm) and in the axoplasm, but absent in the clear vesicles.
采用包埋前免疫电镜细胞化学技术研究了大鼠迷走神经纤维中免疫反应性降钙素基因相关肽(IR-CGRP)的定位。IR-CGRP定位于迷走神经中少数(约5%)有髓纤维和约50%的无髓纤维中。免疫反应性见于致密核心小泡(75 - 150 nm)和轴浆中,但在清亮小泡中未观察到。