Department of Respiratory Medicine, Saiseikai Yokohamashi Tobu Hospital, Japan.
Department of Pathology, Kanagawa Cardiovascular and Respiratory Center, Japan.
Intern Med. 2021 Jan 1;60(1):117-122. doi: 10.2169/internalmedicine.5142-20. Epub 2020 Aug 22.
Idiopathic pulmonary hemosiderosis is characterized by repeated alveolar hemorrhaging. We herein report a 52-year-old Japanese woman who had shortness of breath, diffuse small nodules, thin-walled cysts, and bronchiolectasis. A surgical lung biopsy revealed peribronchial hemosiderosis, centrilobular emphysema, and fragile elastic fibers of the alveolar septa and small vessels. She ultimately underwent living-donor lung transplantation five years after the first visit.
特发性肺含铁血黄素沉着症的特征是反复肺泡出血。我们在此报告一例 52 岁日本女性,其症状为呼吸困难、弥漫性小结节、薄壁囊肿和支气管扩张。外科肺活检显示支气管周围含铁血黄素沉着症、小叶中心性肺气肿和肺泡隔及小血管脆弱的弹性纤维。她在首次就诊五年后最终接受了活体供肺移植。