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(原文中“Applications of”后面缺少具体内容,无法准确完整翻译,仅按现有内容翻译为)在治疗糖尿病患者和减少饮酒方面的应用。

Applications of in treating diabetics and reducing alcohol drinking.

作者信息

Liu Jing, Shi Yeu-Ching, Lee David Yue-Wei

机构信息

Bio-Organic and Natural Products Research Laboratory, Mailman Research Center, McLean Hospital/Harvard Medical School, Belmont, MA 02478, USA.

Taiwan Indigena Botanica, Taipei 10684, China.

出版信息

Chin Herb Med. 2019 Apr;11(2):141-149. doi: 10.1016/j.chmed.2019.04.004. Epub 2019 Apr 5.

DOI:10.1016/j.chmed.2019.04.004
PMID:32831815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7434045/
Abstract

is one of the most important medicinal herbs used traditionally in China. According to (), it has been used traditionally to relieve body heat, eye soring, dry mouth, headache associated with high blood pressure, and stiff neck problems. Modern studies in the 1970s revealed that isoflavonoids extracted from were the bioactive components of an herbal remedy namely Yufeng Ningxin Tablets for the treatment of patients after stroke. This article reviews recent application of in the treatment of diabetics and in reducing alcohol drinking. In view of its low toxicity profile, stands an excellent chance to be developed as a phytomedicine for treating human diseases.

摘要

是中国传统上使用的最重要的草药之一。根据(),它传统上一直用于缓解身体发热、眼睛疼痛、口干、高血压引起的头痛以及颈部僵硬问题。20世纪70年代的现代研究表明,从[草药名称未给出]中提取的异黄酮是一种名为愈风宁心片的草药疗法治疗中风后患者的生物活性成分。本文综述了[草药名称未给出]在治疗糖尿病和减少饮酒方面的最新应用。鉴于其低毒性特征,[草药名称未给出]极有机会被开发成为一种用于治疗人类疾病的植物药。

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2
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3
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