Center for Personalized Health, Northwell Health.
Department of Psychology, University of Minnesota.
Health Psychol. 2020 Sep;39(9):731-735. doi: 10.1037/hea0000897.
This special issue showcases how investigators working in different areas of health behavior change are utilizing early phase studies to advance intervention development. Through the publication of design or protocol papers for currently funded Science of Behavior Change (SOBC) network projects, the special issue illustrates how investigative teams are implementing the experimental medicine approach to advance our understanding of the mechanisms of action that underlie behavior change interventions and, in turn, develop an evidence base that can inform future intervention design. Given that a goal of the experimental medicine approach is the accumulation of an evidence base regarding the links between intervention strategies and putative mechanisms of action, it is critical that this evidence base is readily accessible to investigators and practitioners. Therefore, each of the included articles describes how it is implementing the open-science approach within its study protocol to ensure rigor and reproducibility. Each article provides information about how to register an early phase experiment before study conduct and how to publicly deposit the data, metadata, and publications. The special issue includes 10 design and protocol articles and 2 commentaries on a diverse array of scientific areas and approaches to test mechanisms of action for health behavior change interventions. By disseminating how the National Institutes of Health SOBC Initiative has supported the conduct of early phase intervention studies implementing the experimental medicine and open science approaches, the special issue provides a substantive roadmap to other scientists for how to adopt these approaches. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
本特刊展示了在健康行为改变不同领域工作的研究人员如何利用早期研究来推进干预措施的发展。通过发表目前获得科学行为改变（SOBC）网络项目资助的设计或方案论文，特刊说明了研究团队如何实施实验医学方法来增进我们对行为改变干预措施的作用机制的理解，进而为未来的干预措施设计提供信息基础。鉴于实验医学方法的目标之一是积累关于干预策略和假设作用机制之间联系的证据基础，因此该证据基础必须易于研究人员和从业者获取。因此，每篇文章都描述了其如何在研究方案中实施开放科学方法，以确保严谨性和可重复性。每篇文章都提供了有关如何在研究进行之前注册早期实验以及如何公开存储数据、元数据和出版物的信息。特刊包括 10 篇设计和方案文章以及 2 篇关于各种科学领域和检验健康行为改变干预措施作用机制方法的评论文章。通过传播美国国立卫生研究院 SOBC 计划如何支持实施实验医学和开放科学方法的早期干预研究，特刊为其他科学家提供了一个实质性的路线图，说明如何采用这些方法。（PsycInfo 数据库记录（c）2020 APA，保留所有权利）。
