Hahn H, Kaufmann S H
Immun Infekt. 1977 Jun;5(3):89-94.
Delayed type hypersensitivity is a T-cell-mediated phenomenon. It is characterized by the following features: a) development within 24-72 h after antigen challenge in sensitized individuals, b) perivascular infiltration by mononuclear cells at the inflammatory site, c) transfer by lymphocytes, but not by serum. Delayed type hypersensitivity occurs during infections with facultatively intracellular bacteria and certain viruses, tumor diseases and rejection of transplanted foreign tissue. This article samples evidence that delayed type hypersensitivity is an outward phenomenon indicating the presence of specific T-cells and mononuclear phagocytes, both acting together to produce local immunity which results in the elimination or containment of the noxious agent.
迟发型超敏反应是一种由T细胞介导的现象。它具有以下特征：a）在致敏个体中，抗原激发后24 - 72小时内出现；b）炎症部位有单核细胞的血管周围浸润；c）可由淋巴细胞传递，但不能由血清传递。迟发型超敏反应发生在兼性胞内细菌和某些病毒感染、肿瘤疾病以及移植的异体组织排斥过程中。本文列举证据表明，迟发型超敏反应是一种外在现象，表明存在特异性T细胞和单核吞噬细胞，二者共同作用产生局部免疫，从而导致有害物质的清除或局限。
