Aluja Anton, Malas Olga, Urieta Patricia, Worner Fernando, Balada Ferran
University of Lleida, Catalonia, Spain; Institute of Biomedical Research, Lleida, Catalonia, Spain.
Institute of Biomedical Research, Lleida, Catalonia, Spain.
Physiol Behav. 2020 Dec 1;227:113151. doi: 10.1016/j.physbeh.2020.113151. Epub 2020 Aug 23.
This research studies the relationship between Alexithymia, behavioural, biometric, biochemical and cardiovascular risk in clinical and healthy samples. There were 602 participants (mean age of 52.82 ± 10.59) divided into two groups. The first was made up of 202 patients (165 males and 37 females) who had suffered a cardiovascular disease (CVD), while the second was composed of 400 (285 males and 115 females) healthy volunteers without CVD diagnosis. A cardiovascular risk index (CRI) was developed with the high factorial loading of the following variables: systolic and diastolic blood pressure, total cholesterol/HDL, triglycerides, body mass index, glucose and alcohol and tobacco consumption. The results showed a significant correlation between Alexithymia and the CRI. After controlling for age, sex, occupation, alcohol and tobacco consumption, this correlation decreased, but remained significant for most values. Alexithymia predicted 6% of CRI in the entire sample, once age and sex effect were discounted. Alexithymic subjects with scores above a cut-off point set at higher than 60 had higher levels of glucose, systolic, diastolic, cholesterol/HDL and cardiovascular risk. We discuss that Alexithymia scores contribute to cardiovascular risk, supporting previous findings.
本研究探讨了述情障碍与临床样本及健康样本中的行为、生物特征、生化指标和心血管风险之间的关系。共有602名参与者（平均年龄52.82±10.59岁）被分为两组。第一组由202名患有心血管疾病（CVD）的患者组成（165名男性和37名女性），第二组由400名无CVD诊断的健康志愿者组成（285名男性和115名女性）。通过以下变量的高因子负荷制定了心血管风险指数（CRI）：收缩压和舒张压、总胆固醇/高密度脂蛋白、甘油三酯、体重指数、血糖以及酒精和烟草消费。结果显示述情障碍与CRI之间存在显著相关性。在控制年龄、性别、职业、酒精和烟草消费后，这种相关性有所降低，但对大多数值而言仍具有显著性。一旦排除年龄和性别影响，述情障碍在整个样本中预测了6%的CRI。述情障碍得分高于设定为60以上的临界点的受试者，其血糖、收缩压、舒张压、胆固醇/高密度脂蛋白水平及心血管风险更高。我们讨论了述情障碍得分会导致心血管风险，这支持了先前的研究结果。
