King A T, Lowe K C, Mulligan B J
Department of Zoology, University of Nottingham, U.K.
Adv Exp Med Biol. 1988;222:579-84. doi: 10.1007/978-1-4615-9510-6_70.
PFCs and their emulsions may have value for increasing the efficiency of O2-transport to microbial cultures. Therefore, the effects of emulsion components on growth of S. cerevisiae and E. coli have been examined. Viable cell counts revealed that perfluorodecalin or the commercial emulsion, Fluosol-DA 20%, produced no obvious growth-inhibition over 6h. However, incubation of cells with up to 10% of the Pluronic F-68 surfactant reduced absorbance at 600nm. Further experiments to assess the effects of PFC emulsion components on growth and structure of microbial cells are in progress.
全氟化合物及其乳液在提高向微生物培养物中输送氧气的效率方面可能具有价值。因此,已研究了乳液成分对酿酒酵母和大肠杆菌生长的影响。活细胞计数显示,全氟萘烷或商用乳液Fluosol-DA 20%在6小时内未产生明显的生长抑制作用。然而,用高达10%的普朗尼克F-68表面活性剂孵育细胞会降低600nm处的吸光度。评估全氟化合物乳液成分对微生物细胞生长和结构影响的进一步实验正在进行中。