Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Department of Laboratory Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
J Clin Microbiol. 2020 Oct 21;58(11). doi: 10.1128/JCM.02225-20.
Frequent, low-cost, universal testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with quarantine of those with a positive result has been suggested as a strategy to address the coronavirus disease 2019 (COVID-19) pandemic in the United States. Specifically, home or community use of tests that use paper strip detection devices, which may have reduced sensitivity for SARS-CoV-2, has been advocated. There are several potential challenges or problems with this strategy, including the limited availability of such tests, consequences of incorrect test results, difficulties with adherence to testing, and the questionable accuracy of such tests for detection of infectious people. Because of these, we think it is premature to strongly advocate for such a testing strategy, as the adverse consequences may outweigh any benefits. High-quality outcome data demonstrating the efficacy of this testing strategy are needed before widespread implementation.
频繁、低成本、普遍检测严重急性呼吸综合征冠状病毒 2（SARS-CoV-2），对检测结果呈阳性的人进行隔离，这已被建议作为解决美国 2019 年冠状病毒病（COVID-19）大流行的一种策略。具体而言，提倡在家中或社区使用可能对 SARS-CoV-2 检测敏感性降低的纸条检测设备。这种策略存在几个潜在的挑战或问题，包括此类测试的供应有限、错误测试结果的后果、测试依从性困难以及此类测试对检测传染性人员的准确性存在疑问。正因为如此，我们认为强烈提倡这种检测策略还为时过早，因为其不良后果可能超过任何益处。在广泛实施之前，需要有高质量的结果数据来证明这种检测策略的有效性。
