Chadha Mamta, Si Saibal, Bhatt Devika, Krishnan Sushil, Kumar Rakesh, Bansal Ashok, Sharma Anil Kumar
Department of Anesthesia, Northern Railway Central Hospital, New Delhi, India.
Anesth Essays Res. 2020 Jan-Mar;14(1):87-91. doi: 10.4103/aer.AER_4_20. Epub 2020 Mar 16.
The study is based on the fact that a lower volume of local anesthetic drugs for ultrasound-guided supraclavicular brachial plexus block is useful for upper limb surgeries lasting for a shorter duration, and result in a lower incidence of complications.
The aim of this study is to compare the effectiveness of 35 mL of 0.5% ropivacaine with 20 mL of 0.5% ropivacaine in ultrasound-guided supraclavicular brachial plexus block for upper limb surgery.
Patients undergoing upper limb surgery in an industry-based government hospital in New Delhi, India. Patients were followed in the operation theater and the recovery room.
The study design involves a prospective, double-blind, randomized controlled trial.
A total of 40 participants were recruited for this study. Twenty participants in each group (referred to as group 20 and 30) received 20 mL and 35 mL of 0.5% ropivacaine, respectively, in ultrasound-guided supraclavicular brachial plexus block.
The statistical analysis was performed using the software SPSS version 15 and a value of < 0.05% was considered statistically significant. The statistical tests used included Student's -test to compare values between the two groups for the mean of parametric data, Mann-Whitney U-test for a median of nonparametric data, and Chi-square test or Fisher's exact test for the categorical data.
The sensory and motor block onset in group 20 was 18.06 ± 3.04 and 23.89 ± 2.14 min, respectively. The sensory and motor block onset in group 30 was 17 ± 2.01 and 23.75 ± 2.22 min, respectively. The duration of analgesia in group 20 and 30 was 575.56 ± 104.39 and 730.75 ± 102.09 min, respectively ( < 0.001).
The onset of sensory and motor block of 20 mL of 0.5% ropivacaine is comparable to 35 mL of 0.5% ropivacaine for supraclavicular brachial plexus block for upper limb surgery. There was a 21% decrease in the duration of analgesia with a decrease in volume of 0.5% ropivacaine from 35 mL to 20 mL.
本研究基于这样一个事实，即用于超声引导下锁骨上臂丛神经阻滞的局部麻醉药物用量较低，对持续时间较短的上肢手术有用，且并发症发生率较低。
本研究的目的是比较35毫升0.5%罗哌卡因与20毫升0.5%罗哌卡因在超声引导下锁骨上臂丛神经阻滞用于上肢手术中的有效性。
印度新德里一家基于行业的政府医院中接受上肢手术的患者。在手术室和恢复室对患者进行随访。
研究设计为前瞻性、双盲、随机对照试验。
本研究共招募了40名参与者。每组20名参与者（分别称为20组和30组）在超声引导下锁骨上臂丛神经阻滞中分别接受20毫升和35毫升0.5%罗哌卡因。
使用SPSS 15版软件进行统计分析，P值<0.05%被认为具有统计学意义。所使用的统计检验包括用于比较两组参数数据均值的学生t检验、用于非参数数据中位数的曼-惠特尼U检验以及用于分类数据的卡方检验或费舍尔精确检验。
20组的感觉和运动阻滞起效时间分别为18.06±3.04分钟和23.89±2.14分钟。30组的感觉和运动阻滞起效时间分别为17±2.01分钟和23.75±2.22分钟。20组和30组的镇痛持续时间分别为575.56±104.39分钟和730.75±102.09分钟（P<0.001）。
对于上肢手术的锁骨上臂丛神经阻滞，20毫升0.5%罗哌卡因的感觉和运动阻滞起效时间与35毫升0.5%罗哌卡因相当。随着0.5%罗哌卡因用量从35毫升降至20毫升，镇痛持续时间减少了21%。
