Loeppky J A, Myhre L G, Venters M D, Luft U C
J Appl Physiol Respir Environ Exerc Physiol. 1977 Jun;42(6):803-8. doi: 10.1152/jappl.1977.42.6.803.
Total body water (TBW) was determined on 35 subjects with a tritium (HTO) and an ethanol (ETH) dilution method, the latter using breath analyses for blood ethanol content. Lean body mass (LBM) was estimated by hydrostatic weighing. Mean values for water fraction (TBW/wt) were 0.618 +/- 0.05 with HTO and 0.603 +/- 0.06 with ETH. The difference was not significant. The correlation between the two methods was highly significant (r = 0.90, SEE = 3.5 liters, P less than 0.0001). High correlations were also found between TBW and LBM with either method for TBW (r = 0.94 with HTO, r = 0.91 with ETH). Mean values for TBW/LBM were 0.735 with HTO and 0.717 with ETH. The ETH method compares favorably with the HTO, it has the advantage that it is nonradioactive and can be repeated daily if necessary.
采用氚（HTO）稀释法和乙醇（ETH）稀释法对35名受试者进行了全身水含量（TBW）测定，后者通过呼吸分析来测定血液乙醇含量。通过水下称重法估算瘦体重（LBM）。水含量分数（TBW/体重）的平均值，HTO法为0.618±0.05，ETH法为0.603±0.06。差异不显著。两种方法之间的相关性非常显著（r = 0.90，标准误 = 3.5升，P < 0.0001）。无论采用哪种TBW测定方法，TBW与LBM之间均存在高度相关性（HTO法r = 0.94，ETH法r = 0.91）。TBW/LBM的平均值，HTO法为0.735，ETH法为0.717。ETH法与HTO法相比具有优势，它是非放射性的，如有必要可每日重复测量。
