Ng Wern Hann, Liu Xiang, Mahalingam Suresh
Emerging Viruses, Inflammation and Therapeutics Group, Menzies Health Institute Queensland, Griffith University (Gold Coast Campus), Queensland, Australia.
F1000Res. 2020 Aug 17;9. doi: 10.12688/f1000research.25998.1. eCollection 2020.
COVID-19 emerged in late 2019 and has rapidly spread through many countries globally. The causative SARS-CoV-2 virus was not known until recently, and there is little or no natural immunity in human populations. There is an urgent need for vaccines and drugs to combat this new pandemic. In just a few months, huge efforts and resources by government, academia, and industry have been thrown into the race to develop a vaccine. This brief review summarizes and discusses the array of technologies being applied to vaccine development, highlighting the strengths and weaknesses of the various approaches.
2019年末出现了新型冠状病毒肺炎（COVID-19），并迅速在全球许多国家传播。直到最近才发现致病的严重急性呼吸综合征冠状病毒2（SARS-CoV-2），人群中几乎没有或完全没有天然免疫力。迫切需要疫苗和药物来对抗这一新的大流行病。在短短几个月内，政府、学术界和工业界投入了巨大努力和资源，竞相研发疫苗。本简要综述总结并讨论了应用于疫苗研发的一系列技术，突出了各种方法的优缺点。
