Al-Ghamdi Bandar, Alkaf Fahmi A, Al-Anazi Menwar M, Al Hebaishi Yahya, Al Othimeen Normeen A, Robert Asirvatham Alwin, Ahmed Osman, Alkhushail Abdullah
Department of Cardiology, Prince Sultan Cardiac Center, Riyadh, Saudi Arabia.
Department of Neurology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
SAGE Open Med Case Rep. 2020 Aug 11;8:2050313X20945896. doi: 10.1177/2050313X20945896. eCollection 2020.
Nonbacterial thrombotic endocarditis, a form of noninfectious thrombotic endocarditis, is mainly characterized by deposition of sterile platelet thrombi on heart valves. Usually, it is observed in advanced malignancy. Herein, we report a case of a previously healthy male with recent unprovoked deep vein thrombosis presented with acute ischemic stroke. The echocardiogram revealed aortic and mitral valve masses. Eventually, he was discovered to have advanced cholangiocarcinoma. The present case, apart from being the youngest reported case, is among the few reported cases which manifest the association between cholangiocarcinoma and nonbacterial thrombotic endocarditis.
非细菌性血栓性心内膜炎是一种非感染性血栓性心内膜炎，主要特征是在心脏瓣膜上形成无菌性血小板血栓。通常，它见于晚期恶性肿瘤患者。在此，我们报告一例既往健康的男性，近期无诱因发生深静脉血栓形成，随后出现急性缺血性卒中。超声心动图显示主动脉瓣和二尖瓣有赘生物。最终，他被诊断为晚期胆管癌。该病例不仅是已报道的最年轻病例，也是少数报道的显示胆管癌与非细菌性血栓性心内膜炎之间关联的病例之一。
