Sun Jihang, Chen Chenghao, Peng Yun, Zhang Yue, Tian Hongwei, Yu Jie, Cao Jun, Zeng Qi
Imaging Center Beijing Children's Hospital Capital Medical University National Center for Children's Health Beijing China.
Department of Thoracic Surgery Beijing Children's Hospital Capital Medical University National Center for Children's Health Beijing China.
Pediatr Investig. 2019 Jun 25;3(2):102-109. doi: 10.1002/ped4.12132. eCollection 2019 Jun.
Pectus excavatum (PE) is the most common thoracic wall deformity in children, we need a method which could be used to evaluate pulmonary functions and effects on development.
To evaluate the use of 3D T1-weighted (3DT1) and mDIXON magnetic resonance imaging (MRI) sequences for measuring the thoracic parameters and morphology of children with PE, comparing the measurements with those made on computed tomography (CT).
This is a retrospective study of children with thoracic deformities who were hospitalized at the Department of Thoracic Surgery of the Heart Center, Beijing Children's Hospital, between June 2014 and June 2015. Chest CT was performed first, with the MRI scanning then being performed 0-3 days later. The mDIXON sequences were obtained in inspiratory and expiratory phases and the 3DT1 sequences were obtained during free breathing. Thoracic volume was measured using the acquired images.
The lung volumes measured on mDIXON MRI and CT were highly correlated, with the Haller index not being significantly different between the two methods. Bland-Altman analyses showed that lung, cardiac, and retrosternal parameters were similar between the two methods. Pulmonary parameters were higher with the end-inspiratory phase mDIXON images than with the end-expiratory phase images, as expected, while cardiac parameters were unaffected by the respiratory phase.
Thoracic volumes measured on mDIXON MRI in combination with held respiration could reflect lung volume functions and help in observing the movement functions of the lungs and heart. The method could be used instead of CT, avoiding subjecting the patient to potentially harmful radiation.
漏斗胸（PE）是儿童中最常见的胸壁畸形，我们需要一种可用于评估肺功能及其对发育影响的方法。
评估三维T1加权（3DT1）和多 Dixon 磁共振成像（MRI）序列在测量漏斗胸患儿胸部参数和形态方面的应用，并将测量结果与计算机断层扫描（CT）的测量结果进行比较。
这是一项对2014年6月至2015年6月在北京儿童医院心脏中心胸外科住院的胸廓畸形患儿进行的回顾性研究。首先进行胸部CT检查，然后在0 - 3天后进行MRI扫描。在吸气和呼气阶段获取多 Dixon 序列，在自由呼吸期间获取3DT1序列。使用获取的图像测量胸廓容积。
多 Dixon MRI和CT测量的肺容积高度相关，两种方法的哈勒指数无显著差异。Bland-Altman分析表明，两种方法在肺、心脏和胸骨后参数方面相似。正如预期的那样，吸气末阶段的多 Dixon 图像的肺参数高于呼气末阶段的图像，而心脏参数不受呼吸阶段的影响。
结合屏气进行的多 Dixon MRI测量的胸廓容积可以反映肺容积功能，并有助于观察肺和心脏的运动功能。该方法可替代CT使用，避免让患者受到潜在的有害辐射。
