Plasma Angiotensin Peptide Profiling and ACE (Angiotensin-Converting Enzyme)-2 Activity in COVID-19 Patients Treated With Pharmacological Blockers of the Renin-Angiotensin System.
作者信息
Kintscher Ulrich, Slagman Anna, Domenig Oliver, Röhle Robert, Konietschke Frank, Poglitsch Marko, Möckel Martin
机构信息
From the Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany (U.K., A.S., M.M., R.R., F.K.).
Institute of Pharmacology, Center for Cardiovascular Research, Germany (U.K.).
出版信息
Hypertension. 2020 Nov;76(5):e34-e36. doi: 10.1161/HYPERTENSIONAHA.120.15841. Epub 2020 Aug 27.
Abstract
摘要
相似文献
1
Plasma Angiotensin Peptide Profiling and ACE (Angiotensin-Converting Enzyme)-2 Activity in COVID-19 Patients Treated With Pharmacological Blockers of the Renin-Angiotensin System.接受肾素-血管紧张素系统药理阻滞剂治疗的COVID-19患者的血浆血管紧张素肽谱及ACE（血管紧张素转换酶）-2活性
Hypertension. 2020 Nov;76(5):e34-e36. doi: 10.1161/HYPERTENSIONAHA.120.15841. Epub 2020 Aug 27.
2
Sound Science before Quick Judgement Regarding RAS Blockade in COVID-19.在对COVID-19中的RAS阻断进行快速判断之前的可靠科学依据。
Clin J Am Soc Nephrol. 2020 May 7;15(5):714-716. doi: 10.2215/CJN.03530320. Epub 2020 Mar 27.
3
COVID-19 and RAAS blockers: Could Aliskiren be an appropriate option?2019冠状病毒病与肾素-血管紧张素-醛固酮系统阻滞剂：阿利吉仑会是一个合适的选择吗？
Turk Kardiyol Dern Ars. 2020 Oct;48(7):631-634. doi: 10.5543/tkda.2020.64072.
4
Risk and prognosis of COVID-19 in patients treated with renin-angiotensin-aldosterone inhibitors.接受肾素-血管紧张素-醛固酮抑制剂治疗的COVID-19患者的风险及预后
Eur J Anaesthesiol. 2020 Sep;37(9):739-742. doi: 10.1097/EJA.0000000000001277.
5
The Controversy of Renin-Angiotensin-System Blocker Facilitation Versus Countering COVID-19 Infection.肾素-血管紧张素-系统阻滞剂促进与对抗 COVID-19 感染的争议。
J Cardiovasc Pharmacol. 2020 Oct;76(4):397-406. doi: 10.1097/FJC.0000000000000894.
6
COVID-19 and cardiovascular disease: What we know, what we think we know, and what we need to know.2019冠状病毒病与心血管疾病：我们已知的、我们自认为已知的以及我们需要了解的情况。
J Mol Cell Cardiol. 2020 Jul;144:12-14. doi: 10.1016/j.yjmcc.2020.04.026. Epub 2020 Apr 24.
7
Renin-angiotensin system and SARS-CoV-2 interaction: underlying mechanisms and potential clinical implications.肾素-血管紧张素系统与新型冠状病毒2的相互作用：潜在机制及临床意义
Gen Physiol Biophys. 2020 May;39(3):203-204. doi: 10.4149/gpb_2020019.
8
Intoxication With Endogenous Angiotensin II: A COVID-19 Hypothesis.内源性血管紧张素 II 中毒：COVID-19 假说。
Front Immunol. 2020 Jun 19;11:1472. doi: 10.3389/fimmu.2020.01472. eCollection 2020.
9
Use of Renin-Angiotensin System Blockers During the COVID-19 Pandemic: Early Guidance and Evolving Evidence.2019冠状病毒病大流行期间肾素-血管紧张素系统阻滞剂的使用：早期指南及不断演变的证据
Can J Cardiol. 2020 Aug;36(8):1180-1182. doi: 10.1016/j.cjca.2020.05.033. Epub 2020 Jun 2.
10
A Retrospective Study from 2 Centers in China on the Effects of Continued Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers in Patients with Hypertension and COVID-19.中国 2 家中心回顾性研究：血管紧张素转换酶抑制剂和血管紧张素 II 受体阻滞剂在高血压合并 COVID-19 患者中的持续使用效果。
Med Sci Monit. 2020 Sep 24;26:e926651. doi: 10.12659/MSM.926651.
引用本文的文献
1
Integrated renin angiotensin system dysregulation and immune profiles predict COVID-19 disease severity in a South African cohort.肾素血管紧张素系统综合失调与免疫特征可预测南非队列中新冠肺炎的疾病严重程度。
Sci Rep. 2025 Apr 14;15(1):12799. doi: 10.1038/s41598-025-96161-w.
2
The Relation of Angiotensin-Converting Enzyme 2, Renin-Angiotensin-Aldosterone System Inhibitors, and Arterial Stiffness in Acute COVID-19 Emergency Department Patients-A Prospective Observational Study.急性新冠肺炎急诊科患者中血管紧张素转换酶2、肾素-血管紧张素-醛固酮系统抑制剂与动脉僵硬度的关系——一项前瞻性观察研究
J Clin Med. 2025 Mar 25;14(7):2233. doi: 10.3390/jcm14072233.
3
Renin-angiotensin-aldosterone system activation in plasma as marker for prognosis in critically ill patients with COVID-19: a prospective exploratory study.血浆肾素-血管紧张素-醛固酮系统激活作为COVID-19危重症患者预后的标志物：一项前瞻性探索性研究
Ann Intensive Care. 2025 Jan 16;15(1):10. doi: 10.1186/s13613-025-01433-3.
4
Mathematical modeling of impacts of patient differences on renin-angiotensin system and applications to COVID-19 lung fibrosis outcomes.患者差异对肾素-血管紧张素系统影响的数学建模及其在COVID-19肺纤维化结局中的应用
Comput Biol Med. 2025 Mar;186:109631. doi: 10.1016/j.compbiomed.2024.109631. Epub 2025 Jan 2.
5
Evaluation of angiotensin converting enzyme 2 (ACE2), angiotensin II (Ang II), miR-141-3p, and miR-421 levels in SARS-CoV-2 patients: a case-control study.评估 SARS-CoV-2 患者血管紧张素转换酶 2（ACE2）、血管紧张素 II（Ang II）、miR-141-3p 和 miR-421 水平：一项病例对照研究。
BMC Infect Dis. 2024 Apr 22;24(1):429. doi: 10.1186/s12879-024-09310-3.
6
Comparison of Different Vascular Biomarkers for Predicting In-Hospital Mortality in Severe SARS-CoV-2 Infection.用于预测重症新型冠状病毒2型感染患者院内死亡率的不同血管生物标志物的比较
Microorganisms. 2024 Jan 22;12(1):229. doi: 10.3390/microorganisms12010229.
7
Levels of Angiotensin and Kinin Metabolite Peptides Related to COVID-19 Severity.与新冠病毒疾病严重程度相关的血管紧张素和激肽代谢产物肽水平
ACS Pharmacol Transl Sci. 2023 Dec 13;7(1):186-194. doi: 10.1021/acsptsci.3c00227. eCollection 2024 Jan 12.
8
Proteomic Evolution from Acute to Post-COVID-19 Conditions.从急性到新冠后(post-COVID-19)条件的蛋白质组学演变。
J Proteome Res. 2024 Jan 5;23(1):52-70. doi: 10.1021/acs.jproteome.3c00324. Epub 2023 Dec 4.
9
Renin-angiotensin system inhibitor discontinuation in COVID-19 did not modify systemic ACE2 in a randomized controlled trial.在一项随机对照试验中，新冠病毒病患者停用肾素-血管紧张素系统抑制剂并未改变全身血管紧张素转换酶2水平。
iScience. 2023 Oct 5;26(11):108146. doi: 10.1016/j.isci.2023.108146. eCollection 2023 Nov 17.
10
The effect of taurine supplementation on the renin-angiotensin-aldosterone system of dogs with congestive heart failure.牛磺酸补充对充血性心力衰竭犬肾素-血管紧张素-醛固酮系统的影响。
Sci Rep. 2023 Jul 3;13(1):10700. doi: 10.1038/s41598-023-37978-1.
本文引用的文献
1
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.新型冠状病毒肺炎的肺血管内皮细胞炎症、血栓形成和血管生成。
N Engl J Med. 2020 Jul 9;383(2):120-128. doi: 10.1056/NEJMoa2015432. Epub 2020 May 21.
2
Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Covid-19.肾素-血管紧张素-醛固酮系统抑制剂与新冠病毒风险。
N Engl J Med. 2020 Jun 18;382(25):2441-2448. doi: 10.1056/NEJMoa2008975. Epub 2020 May 1.
3
Renin-Angiotensin-Aldosterone System Blockers and the Risk of Covid-19.肾素-血管紧张素-醛固酮系统阻滞剂与新冠病毒风险。
N Engl J Med. 2020 Jun 18;382(25):2431-2440. doi: 10.1056/NEJMoa2006923. Epub 2020 May 1.
4
Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19.新冠病毒病患者中的肾素-血管紧张素-醛固酮系统抑制剂
N Engl J Med. 2020 Apr 23;382(17):1653-1659. doi: 10.1056/NEJMsr2005760. Epub 2020 Mar 30.
5
Angs (Angiotensins) of the Alternative Renin-Angiotensin System Predict Outcome in Patients With Heart Failure and Preserved Ejection Fraction.替代肾素-血管紧张素系统的血管紧张素（Angs）可预测射血分数保留的心力衰竭患者的结局。
Hypertension. 2019 Aug;74(2):285-294. doi: 10.1161/HYPERTENSIONAHA.119.12786. Epub 2019 Jun 24.
Zotero 插件