North Middlesex University Hospital and St Bartholomew's Hospital, London, UK.
Geisinger Heart Institute, Wilkes-Barre, Pennsylvania.
Pacing Clin Electrophysiol. 2021 Jan;44(1):5-14. doi: 10.1111/pace.14050. Epub 2020 Sep 7.
His-Purkinje conduction system pacing (HPCSP) in the form of His bundle pacing (HBP) and left bundle branch pacing (LBBP) allows normal left ventricular activation, thereby preventing the adverse consequences of right ventricular pacing. HBP has been established for several years with centers from China, Europe, and North America reporting their experience. There is international guidance as to how to implant such systems with the differing patterns of His bundle capture clearly described. LBBP is a more recent innovation with potential advantages including improved pacing parameters. HPCSP has been extensively studied in a variety of indications including cardiac resynchronization therapy, atrioventricular node ablation, and bradycardia pacing. This review will focus on the clinical outcomes of HPCSP including mortality and morbidity of heart failure hospitalization and symptoms.
希氏束起搏（HBP）和左束支起搏（LBBP）形式的 His-Purkinje 传导系统起搏（HPCSP）可实现正常的左心室激活，从而防止右心室起搏的不良后果。HBP 已经存在了几年，来自中国、欧洲和北美的中心都报告了他们的经验。国际上有关于如何植入此类系统的指南，清楚地描述了希氏束夺获的不同模式。LBBP 是一种较新的创新，具有潜在的优势，包括改善起搏参数。HPCSP 已在多种适应症中进行了广泛研究，包括心脏再同步治疗、房室结消融和心动过缓起搏。本综述将重点介绍 HPCSP 的临床结果，包括心力衰竭住院和症状的死亡率和发病率。
