Ezzeddine Fatima M, Leon Isaac G, Cha Yong-Mei
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, US.
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, US.
Arrhythm Electrophysiol Rev. 2023 Aug 11;12:e22. doi: 10.15420/aer.2023.03. eCollection 2023.
To date, biventricular pacing (BiVP) has been the standard pacing modality for cardiac resynchronisation therapy. However, it is non-physiological, with the activation spreading between the left ventricular epicardium and right ventricular endocardium. Up to one-third of patients with heart failure who are eligible for cardiac resynchronisation therapy do not derive benefit from BiVP. Conduction system pacing (CSP), which includes His bundle pacing and left bundle branch area pacing, has emerged as an alternative to BiVP for cardiac resynchronisation. There is mounting evidence supporting the benefits of CSP in achieving synchronous ventricular activation and repolarisation. The aim of this review is to summarise the current options and outcomes of CSP when used for cardiac resynchronisation in patients with heart failure.
迄今为止，双心室起搏（BiVP）一直是心脏再同步治疗的标准起搏方式。然而，它不符合生理情况，激动在左心室心外膜和右心室心内膜之间传播。符合心脏再同步治疗条件的心力衰竭患者中，多达三分之一无法从双心室起搏中获益。传导系统起搏（CSP），包括希氏束起搏和左束支区域起搏，已成为双心室起搏用于心脏再同步治疗的替代方法。越来越多的证据支持传导系统起搏在实现心室同步激动和复极方面的益处。本综述的目的是总结传导系统起搏用于心力衰竭患者心脏再同步治疗时的当前选择和结果。
