Bulte Camille A, Hoegler Karl M, Khachemoune Amor
Department of Dermatology, University of Maryland Medical Center, Baltimore, Maryland, USA.
Brooklyn Campus of the VA NY Harbor Healthcare System, Brooklyn, New York, USA.
Dermatol Ther. 2020 Nov;33(6):e14236. doi: 10.1111/dth.14236. Epub 2020 Sep 15.
A collision tumor is a neoplastic lesion comprised of two or more distinct cell populations that maintain distinct borders. Collision tumors, which are rare but well documented, can be composed of two benign tumors, a benign and malignant tumor, and two malignant tumors. Although case reports and reviews on specific types of collision tumors exist, a cohesive source discussing these tumors is lacking. We critically reviewed the literature by analyzing case reports and retrospective studies in order to evaluate the following regarding collision tumors: definitions, types, pathogenesis, diagnosis, and management. Reports of these tumors are infrequent but not insignificant, and accurate classification and diagnosis will lead to better patient outcomes.
碰撞瘤是一种肿瘤性病变，由两个或更多保持清晰边界的不同细胞群组成。碰撞瘤虽然罕见但有充分记录，可由两个良性肿瘤、一个良性和一个恶性肿瘤以及两个恶性肿瘤组成。尽管存在关于特定类型碰撞瘤的病例报告和综述，但缺乏一个全面讨论这些肿瘤的资料来源。我们通过分析病例报告和回顾性研究对文献进行了严格审查，以便评估碰撞瘤的以下方面：定义、类型、发病机制、诊断和治疗。这些肿瘤的报告虽不常见但并非无足轻重，准确的分类和诊断将带来更好的患者预后。
