Siraj Fouzia, Shruti Sharma, Jain Sonam, Bhatnagar Amar, Agrawal Usha
Department of Pathology, National Institute of Pathology, NEW DELHI, INDIA.
Turk Patoloji Derg. 2019;35(3):237-241. doi: 10.5146/tjpath.2017.01397.
The term collision tumor is used to describe two neoplasms occurring in the same anatomic location with juxtaposition of different tumor elements. Such a coexistence of tumors anywhere in the body is relatively rare. We report a case of 32-year-old female with collision tumor of rectum. The tumor showed two distinct histological patterns with predominant component consisting of malignant melanoma and a minor component of squamous cell carcinoma. The morphological picture of collision was further confirmed by specific immunohistochemical profile of the two tumors. Collision tumors of rectum are uncommon with most of the reported cases comprising adenocarcinoma and neuroendocrine tumors. To the best of our knowledge this is the first case of collision tumor of malignant melanoma and squamous cell carcinoma in the rectum.
“碰撞瘤”一词用于描述发生在同一解剖部位、不同肿瘤成分并列的两种肿瘤。这种肿瘤在体内任何部位同时存在的情况相对罕见。我们报告一例32岁女性直肠碰撞瘤病例。该肿瘤呈现出两种不同的组织学模式，主要成分是恶性黑色素瘤，次要成分是鳞状细胞癌。两种肿瘤的特异性免疫组化特征进一步证实了碰撞的形态学表现。直肠碰撞瘤并不常见，大多数报道的病例包括腺癌和神经内分泌肿瘤。据我们所知，这是首例直肠恶性黑色素瘤与鳞状细胞癌碰撞瘤的病例。
