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Letter: optimising response to ustekinumab therapy for patients with Crohn's disease.

作者信息

Hudson Joshua, Herfarth Hans H, Barnes Edward L

机构信息

Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.

Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.

出版信息

Aliment Pharmacol Ther. 2020 Sep;52(5):906. doi: 10.1111/apt.15961.

DOI:10.1111/apt.15961
PMID:32852815
Abstract
摘要

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Ustekinumab Dosing Individualization in Crohn's Disease Guided by a Population Pharmacokinetic-Pharmacodynamic Model.基于群体药代动力学-药效学模型指导的克罗恩病中优特克单抗给药个体化
Pharmaceutics. 2021 Sep 30;13(10):1587. doi: 10.3390/pharmaceutics13101587.
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Effectiveness of Reinduction and/or Dose Escalation of Ustekinumab in Crohn's Disease: A Systematic Review and Meta-analysis.
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Clin Gastroenterol Hepatol. 2022 Dec;20(12):2728-2740.e1. doi: 10.1016/j.cgh.2021.10.002. Epub 2021 Oct 8.