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使用非接触式雷达技术和机器学习(Somnofy®)对睡眠阶段分类进行验证。

Validation of sleep stage classification using non-contact radar technology and machine learning (Somnofy®).

作者信息

Toften Ståle, Pallesen Ståle, Hrozanova Maria, Moen Frode, Grønli Janne

机构信息

Department of Data Science, VitalThings AS, Tønsberg, Norway.

Department of Psychosocial Science, University of Bergen, Bergen, Norway; Norwegian Competence Center for Sleep Disorders, Haukeland University Hospital, Bergen, Norway.

出版信息

Sleep Med. 2020 Nov;75:54-61. doi: 10.1016/j.sleep.2020.02.022. Epub 2020 Mar 6.

DOI:10.1016/j.sleep.2020.02.022
PMID:32853919
Abstract

OBJECTIVE

To validate automatic sleep stage classification using deep neural networks on sleep assessed by radar technology in the commercially available sleep assistant Somnofy® against polysomnography (PSG).

METHODS

Seventy-one nights of overnight sleep in healthy individuals were assessed by both PSG and Somnofy at two different institutions. The Somnofy unit was placed in two different locations per room (nightstand and wall). The sleep algorithm was validated against PSG using a 25-fold cross validation technique, and performance was compared to the inter-rater reliability between the PSG sleep scored by two independent sleep specialists.

RESULTS

Epoch-by-epoch analyses showed a sensitivity (accuracy to detect sleep) and specificity (accuracy to detect wake) for Somnofy of 0.97 and 0.72 respectively, compared to 0.99 and 0.85 for the PSG scorers. The sleep stage differentiation for Somnofy was 0.75 for N1/N2, 0.74 for N3 and 0.78 for R, whilst PSG scorers ranged between 0.83 and 0.96. The intraclass correlation coefficient revealed excellent and good reliability for total sleep time and sleep efficiency, while sleep onset and R latency had poor agreement. Somnofy underestimated total wake time by 5 min and N1/N2 by 3 min. N3 was overestimated by 4 min and R by 3 min. Results were independent of institution and sensor location.

CONCLUSION

Somnofy showed a high accuracy staging sleep in healthy individuals and has potential to assess sleep quality and quantity in a sample of healthy, mostly young adults. More research is needed to examine performance in children, older individuals and those with sleep disorders.

摘要

目的

在市售睡眠辅助设备Somnofy®中,利用雷达技术评估睡眠时,通过深度神经网络验证自动睡眠阶段分类与多导睡眠图(PSG)的对比情况。

方法

在两个不同机构,对71名健康个体的夜间睡眠进行了PSG和Somnofy评估。Somnofy设备在每个房间的两个不同位置(床头柜和墙壁)放置。使用25折交叉验证技术,对照PSG对睡眠算法进行验证,并将性能与两名独立睡眠专家对PSG睡眠评分的评分者间信度进行比较。

结果

逐时段分析显示,Somnofy检测睡眠的敏感性(检测睡眠的准确性)和特异性(检测清醒的准确性)分别为0.97和0.72,而PSG评分者分别为0.99和0.85。Somnofy对N1/N2睡眠阶段的区分度为0.75,N3为0.74,快速眼动(R)睡眠为0.78,而PSG评分者的区分度在0.83至0.96之间。组内相关系数显示,总睡眠时间和睡眠效率具有极佳和良好的信度,而入睡时间和R期潜伏期的一致性较差。Somnofy低估总清醒时间5分钟,N1/N2睡眠阶段低估3分钟。N3睡眠阶段高估4分钟,R期睡眠高估3分钟。结果不受机构和传感器位置的影响。

结论

Somnofy在健康个体中显示出较高的睡眠分期准确性,有潜力在健康的、大多为年轻成年人的样本中评估睡眠质量和数量。需要更多研究来检验其在儿童、老年人和睡眠障碍患者中的性能。

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