IEEE J Biomed Health Inform. 2021 Oct;25(10):3844-3853. doi: 10.1109/JBHI.2021.3072644. Epub 2021 Oct 5.
Manual scoring of sleep stages from polysomnography (PSG) records is essential to understand the sleep quality and architecture. Since the PSG requires specialized personnel, a lab environment, and uncomfortable sensors, non-contact sleep staging methods based on machine learning techniques have been investigated over the past years. In this study, we propose an attention-based bidirectional long short-term memory (Attention Bi-LSTM) model for automatic sleep stage scoring using an impulse-radio ultra-wideband (IR-UWB) radar which can remotely detect vital signs. Sixty-five young (30.0 ± 8.6 yrs.) and healthy volunteers underwent nocturnal PSG and IR-UWB radar measurement simultaneously; From 51 recordings, 26 were used for training, 8 for validation, and 17 for testing. Sixteen features including movement-, respiration-, and heart rate variability-related indices were extracted from the raw IR-UWB signals in each 30-s epoch. Sleep stage classification performances of Attention Bi-LSTM model with optimized hyperparameters were evaluated and compared with those of conventional LSTM networks for same test dataset. In the results, we achieved an accuracy of 82.6 ± 6.7% and a Cohen's kappa coefficient of 0.73 ± 0.11 in the classification of wake stage, REM sleep, light (N1+N2) sleep, and deep (N3) sleep which is significantly higher than the conventional LSTM networks (p < 0.01). Moreover, the classification performances were higher than those reported in comparative studies, demonstrating the effectiveness of the attention mechanism coupled with bi-LSTM networks for the sleep staging using cardiorespiratory signals.
多导睡眠图 (PSG) 记录的睡眠阶段手动评分对于了解睡眠质量和结构至关重要。由于 PSG 需要专业人员、实验室环境和不舒服的传感器,因此近年来已经研究了基于机器学习技术的非接触式睡眠分期方法。在这项研究中,我们提出了一种基于注意力的双向长短时记忆 (Attention Bi-LSTM) 模型,用于使用能够远程检测生命体征的脉冲无线电超宽带 (IR-UWB) 雷达进行自动睡眠阶段评分。六十五名年轻(30.0 ± 8.6 岁)和健康志愿者同时进行夜间 PSG 和 IR-UWB 雷达测量;从 51 次记录中,26 次用于训练,8 次用于验证,17 次用于测试。从每个 30 秒的原始 IR-UWB 信号中提取了 16 个特征,包括运动、呼吸和心率变异性相关指标。使用优化后的超参数评估了 Attention Bi-LSTM 模型的睡眠阶段分类性能,并与传统 LSTM 网络在相同的测试数据集上进行了比较。结果表明,在清醒阶段、REM 睡眠、浅(N1+N2)睡眠和深(N3)睡眠的分类中,我们实现了 82.6 ± 6.7%的准确率和 0.73 ± 0.11 的 Cohen's kappa 系数,明显高于传统 LSTM 网络(p < 0.01)。此外,分类性能高于比较研究中的报告结果,表明注意力机制与双向长短时记忆网络结合用于基于心肺信号的睡眠分期是有效的。