TOBB ETU Medical School, Department of Ophthalmology, Ankara, Turkey.
Hatay State Hospital, Clinic of Ophthalmology, Hatay, Turkey.
Turk J Ophthalmol. 2020 Aug 26;50(4):211-215. doi: 10.4274/tjo.galenos.2020.29939.
To evaluate the early effects of femtosecond laser-assisted in situ keratomileusis (LASIK) surgery on retinal ganglion cell thickness (GCT), peripapillary retinal nerve fiber thickness (NFT), and central macular thickness (CMT) obtained by spectral domain optical coherence tomography (SD-OCT) in a healthy population.
This case-control study included data from the right eye of 40 subjects without any disease other than refractive error and who had undergone femtosecond LASIK surgery. The preoperative, postoperative 1-hour, and postoperative 3-week GCT, NFT, and CMT values obtained by SD-OCT were compared.
The mean age was 27.54±5.99 years (18-45 years). GCT, NFT, and CMT were 18.43±6.03 μm, 107.90±9.01, and 234.3±21.2 μm preoperatively; 18.05±5.93 μm, 108.08±8.92 μm, and 230.1±22.6 μm at postoperative 1 hour; and 17.86±5.27 μm, 107.98±10.13, and 236.3±25.1 μm at postoperative 3 weeks (p=0.159, 0.85, and 0.254, respectively).
There were no changes in GCT, NFT, and CMT values evaluated with SD-OCT in the early period after femtosecond LASIK surgery.
评估飞秒激光辅助原位角膜磨镶术（LASIK）对健康人群中视网膜神经节细胞厚度（GCT）、视盘周围视网膜神经纤维层厚度（NFT）和中心黄斑厚度（CMT）的早期影响，这些参数通过谱域光学相干断层扫描（SD-OCT）获得。
本病例对照研究纳入了 40 名除屈光不正外无其他疾病且接受飞秒 LASIK 手术的受试者的右眼数据。比较了术前、术后 1 小时和术后 3 周的 SD-OCT 获得的 GCT、NFT 和 CMT 值。
平均年龄为 27.54±5.99 岁（18-45 岁）。术前 GCT、NFT 和 CMT 分别为 18.43±6.03μm、107.90±9.01μm 和 234.3±21.2μm；术后 1 小时分别为 18.05±5.93μm、108.08±8.92μm 和 230.1±22.6μm；术后 3 周分别为 17.86±5.27μm、107.98±10.13μm 和 236.3±25.1μm（p=0.159、0.85 和 0.254）。
在飞秒 LASIK 手术后的早期，SD-OCT 评估的 GCT、NFT 和 CMT 值没有变化。
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