Department of Neurology, Klinikum Ingolstadt, Krumenauerstrasse 25, 85049, Ingolstadt, Germany.
Department of Neurology, Asklepios Klinik Altona, Hamburg, Germany.
J Neurol. 2021 Feb;268(2):502-505. doi: 10.1007/s00415-020-10188-9. Epub 2020 Aug 28.
In this retrospective observational study and referring to a historical case presented in 2009, we searched for typical clinical and imaging features of brainstem encephalitis in neuroborreliosis.
In addition to the historical case we describe five affected patients.
All patients had a very similar prolonged clinical course with unspecific symptoms such as wasting, fatigue and headache. Brainstem signs were irregularly observed. MRI showed symmetrical brainstem alterations in all patients. In coronary FLAIR imaging these changes formed a figure resembling a Philippine tarsier.
A subset of patients with neuroborreliosis develops a brainstem encephalitis with a typical clinical course and distinct MRI findings.
在这项回顾性观察研究中，我们参考了 2009 年报告的一个病例，寻找神经莱姆病中脑干脑炎的典型临床和影像学特征。
除了描述的历史病例，我们还描述了五名受影响的患者。
所有患者的临床病程都非常相似，表现为非特异性症状，如消瘦、疲劳和头痛。脑干体征不规则出现。MRI 显示所有患者的脑干均有对称性改变。在冠状面 FLAIR 成像中，这些变化形成了类似于菲律宾眼镜猴的图像。
神经莱姆病的患者中有一部分会发展为具有典型临床病程和独特 MRI 表现的脑干脑炎。
