von Heijne G
Department of Molecular Biology, Karolinska Institutet, Huddinge University Hospital, Sweden.
Biochim Biophys Acta. 1988 Jun 9;947(2):307-33. doi: 10.1016/0304-4157(88)90013-5.
In the living cell, proteins are efficiently sorted to a whole range of subcellular compartments. In many cases, sorting specificity is mediated by short 'sorting signals' attached either permanently or transiently to the protein. At long last, a fairly coherent picture of the design and function of many such sorting signals is beginning to emerge.
在活细胞中，蛋白质能被高效地分选到一系列亚细胞区室中。在许多情况下，分选特异性是由永久性或临时性附着在蛋白质上的短“分选信号”介导的。最终，许多此类分选信号的设计与功能的相当连贯的图景开始浮现出来。
