Li Zhi, Zhang Hongmin, Zha Qingbing, Zhai Chunyang, Li Wanbin, Zeng Lixi, Zhu Mingshan
Guangdong Key Laboratory of Environmental Pollution and Health, School of Environment, Jinan University, Guangzhou, 511443, People's Republic of China.
School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, 315211, People's Republic of China.
Mikrochim Acta. 2020 Aug 28;187(9):526. doi: 10.1007/s00604-020-04524-z.
A new photo-electrochemical sensor based on MIL-101(Cr) MOF/carbon black (CB) is fabricated and characterized. By using differential pulse voltammetry, dopamine (DA) can be effectively detected using a photo-electrochemical MIL-101(Cr)/CB sensor under visible light. The CB acts as the electron bridge to combine with the large specific surface area and photo-catalytic feature of MOF, which contribute to the improvements of sensitivity of DA detection. The concentration of the catalyst, pH value, accumulation potential, and accumulation time were also optimized. Furthermore, the electrochemical performances of MIL-101(Cr)/CB sensor was investigated by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), scan rate, electrochemically active surface area (ECSA), and amperometric responses. A detection limit of 0.38 nM (LOD = 3 s/S, s = 0.028) and a working range of 1 nM to 2.22 μM has been achieved. The MIL-101(Cr)/CB sensor exhibits excellent reproducibility, stability, and selectivity and also has satisfactory recovery rate for the analysis of real samples including calf serum and human urine. Graphical abstract.
制备并表征了一种基于MIL-101(Cr)金属有机框架/炭黑（CB）的新型光电化学传感器。通过差分脉冲伏安法，在可见光下使用光电化学MIL-101(Cr)/CB传感器可有效检测多巴胺（DA）。炭黑充当电子桥，与金属有机框架的大比表面积和光催化特性相结合，有助于提高多巴胺检测的灵敏度。还对催化剂浓度、pH值、富集电位和富集时间进行了优化。此外，通过循环伏安法（CV）、电化学阻抗谱（EIS）、扫描速率、电化学活性表面积（ECSA）和安培响应研究了MIL-101(Cr)/CB传感器的电化学性能。实现了0.38 nM的检测限（LOD = 3s/S，s = 0.028）和1 nM至2.22 μM的工作范围。MIL-101(Cr)/CB传感器具有出色的重现性、稳定性和选择性，对包括小牛血清和人尿液在内的实际样品分析也具有令人满意的回收率。图形摘要。
