Department of Pediatric Dentistry, University of Cruzeiro do Sul, São Paulo, Brazil.
Department of Morphology and Genetics, Federal University of São Paulo, São Paulo, Brazil.
Eur Arch Paediatr Dent. 2021 Jun;22(3):387-392. doi: 10.1007/s40368-020-00559-1. Epub 2020 Aug 28.
To assess the efficacy of silver diamine fluoride (SDF) and sodium fluoride (NaF) in inhibiting enamel erosion in primary teeth.
80 primary canine teeth were immersed for 24 h in 2% NaF, 10% SDF, or distilled water. Afterward, some of them underwent a 10-min acid challenge using either 1% or 10% citric acid while others did not. Specimens selected for negative controls were immersed in distilled water but not exposed to the acids, whereas those selected for positive controls were not only immersed in distilled water, but also exposed to the acids. Following, 3-mL samples were collected for calcium and phosphorus analysis by an atomic emission spectrometer.
1% acid caused higher phosphorus loss in the positive control group than in the others (no differences between them). Regarding 10% acid, the SDF group showed lower phosphorus loss compared to the positive control and NaF groups. From calcium loss analysis, SDF and NaF groups presented no significant difference when compared to the positive control groups after both acidic challenges.
Considering phosphorus loss values, 10% SDF seems to be effective in inhibiting enamel erosion after 1% and 10% citric acid challenges, whereas 2% NaF only after 1% citric acid challenge. Regarding calcium loss values, both fluoride agents seem to have no impact on inhibiting enamel erosion after 1% and 10% citric acid challenges.
评估氟化银（SDF）和氟化钠（NaF）抑制乳牙釉质侵蚀的效果。
80 颗乳犬牙浸泡在 2%的 NaF、10%的 SDF 或蒸馏水中 24 小时。之后，部分牙齿经 1%或 10%柠檬酸作用 10 分钟后进行酸蚀挑战，其余牙齿则未经酸蚀处理。阴性对照组的标本浸泡在蒸馏水中但不暴露于酸液中，阳性对照组的标本不仅浸泡在蒸馏水中，而且暴露于酸液中。然后，用原子发射光谱仪收集 3ml 样本进行钙和磷分析。
1%的酸对阳性对照组的磷损失影响较大，与其他组相比有显著差异（其他组之间无差异）。而对于 10%的酸，SDF 组的磷损失明显低于阳性对照组和 NaF 组。从钙损失分析来看，SDF 和 NaF 组在两次酸蚀挑战后与阳性对照组相比均无显著差异。
从磷损失值来看，10%的 SDF 似乎能有效抑制 1%和 10%柠檬酸作用后的釉质侵蚀，而 2%的 NaF 仅能抑制 1%柠檬酸作用后的釉质侵蚀。从钙损失值来看，两种氟化物制剂在 1%和 10%柠檬酸作用后对抑制釉质侵蚀似乎没有影响。
