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磁悬浮系统在疾病诊断中的应用。

Magnetic Levitation Systems for Disease Diagnostics.

机构信息

Department of Radiology and Precision Health Program, Michigan State University, East Lansing, MI, USA.

Department of Radiology and Precision Health Program, Michigan State University, East Lansing, MI, USA.

出版信息

Trends Biotechnol. 2021 Mar;39(3):311-321. doi: 10.1016/j.tibtech.2020.07.010. Epub 2020 Aug 27.

Abstract

Magnetic levitation (MagLev) is a well-documented, robust technique for density measurements and separations. Although the potential of MagLev as an emerging tool in biotechnology has been recently investigated, the practical use of MagLev in diagnosis and disease detection merits further attention. This review highlights the diagnostic capacity of a simple and portable MagLev system and the possibilities and limitations of the MagLev technique for density-based separation, classification, and manipulation of soft matter and biological systems (e.g., cells, proteins), which in turn may pave the way for the discovery of disease-specific biomarkers.

摘要

磁悬浮(MagLev)是一种经过充分记录和验证的密度测量和分离技术。尽管 MagLev 作为生物技术中新兴工具的潜力最近已被研究,但 MagLev 在诊断和疾病检测中的实际应用值得进一步关注。本综述强调了简单便携的 MagLev 系统的诊断能力,以及 MagLev 技术在基于密度的分离、分类和操纵软物质和生物系统(例如细胞、蛋白质)方面的可能性和局限性,这反过来可能为发现疾病特异性生物标志物铺平道路。

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