Ann and Robert H. Lurie Children's Hospital, Chicago, IL.
Ann and Robert H. Lurie Children's Hospital, Chicago, IL; Feinberg School of Medicine, Northwestern University, Chicago, IL.
J Pediatr. 2021 Jan;228:294-296. doi: 10.1016/j.jpeds.2020.08.067. Epub 2020 Aug 27.
We present 4 pediatric patients with trisomy 21 (T21) and associated comorbidities who developed coronavirus disease 2019 requiring hospitalization. A review of the literature revealed that comorbidities associated with T21 may predispose patients to severe disease. Children with T21 should be considered high risk and monitored carefully if infected with severe acute respiratory syndrome coronavirus 2.
我们报告了 4 例唐氏综合征（T21）合并其他合并症的儿科患者，他们因感染 2019 年冠状病毒病需要住院治疗。对文献的回顾表明，T21 相关的合并症可能使患者易患严重疾病。如果感染严重急性呼吸综合征冠状病毒 2，T21 患儿应被视为高危人群，并密切监测。
