磁共振成像对前庭神经鞘瘤患者的诊断评估：系统评价。

Diagnostic assessment of magnetic resonance imaging for patients with intralabyrinthine schwannoma: A systematic review.

机构信息

Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

出版信息

J Neuroradiol. 2022 Jan;49(1):41-46. doi: 10.1016/j.neurad.2020.08.002. Epub 2020 Aug 27.

DOI:10.1016/j.neurad.2020.08.002

PMID:32861774

Abstract

OBJECTIVES

Recent advancements in high-resolution imaging have improved the diagnostic assessment of magnetic resonance imaging (MRI) for intralabyrinthine schwannoma (ILS). This systematic review aimed to evaluate the diagnostic performance of MRI for patients with ILS.

METHODS

Ovid-MEDLINE and EMBASE databases were searched for related studies on the diagnostic performance of MRI for patients with ILS published up to February 10, 2020. The primary endpoint was the diagnostic performance of MRI for ILS. The quality of the enrolled studies was assessed using tailored questionnaires and the Quality Assessment of Diagnostic Accuracy Studies-2 criteria.

RESULTS

Overall, 6 retrospective studies that included 122 patients with ILS from a parent population of 364 were included. The sample size, parent population and its composition, reference standard, detailed parameters of MRI, and even the diagnostic methods varied between the studies. The studies had moderate quality. The sensitivity of combination of T2WI and CE-T1WI was over 90%. Relative sensitivity of T2WI comparative to CE-T1WI ranged from 62% to 100%, and the specificity were 100%.

CONCLUSIONS

MRI has acceptable diagnostic performance for ILS. There is a need for well-organized research to reduce the factors causing heterogeneity.

摘要

目的

高分辨率成像技术的最新进展提高了磁共振成像（MRI）对内淋巴囊神经鞘瘤（ILS）的诊断评估能力。本系统评价旨在评估 MRI 对 ILS 患者的诊断性能。

方法

检索 Ovid-MEDLINE 和 EMBASE 数据库，以获取截至 2020 年 2 月 10 日发表的关于 MRI 对 ILS 患者诊断性能的相关研究。主要终点是 MRI 对 ILS 的诊断性能。使用专门的问卷和诊断准确性研究质量评估-2 标准评估纳入研究的质量。

结果

共纳入 6 项回顾性研究，这些研究共纳入了 122 例来自 364 例母群体的 ILS 患者。研究之间的样本量、母群体及其构成、参考标准、MRI 的详细参数甚至诊断方法均存在差异。这些研究的质量为中等。T2WI 和 CE-T1WI 联合的敏感度超过 90%。T2WI 与 CE-T1WI 相比的相对敏感度范围为 62%至 100%，特异性为 100%。