Di Lullo Antonella Miriam, Paolucci Aldo, Motta Sergio, Cantone Elena, Barbieri Emiliano, Cicala Domenico, Grassi Roberta, Bruno Federico, Splendiani Alessandra, Tortora Fabio, Cavaliere Michele, Brunese Luca
Department of Neuroscience, Reproductive and Odontostomatologic Sciences, University of Naples "Federico II", and CEINGE- Advanced Biotechnology, Naples, Italy.
Ospedale Maggiore Policlinico Milano, Milan, Italy.
Acta Biomed. 2020 Jul 13;91(8-S):136-144. doi: 10.23750/abm.v91i8-S.9976.
Intralabyrinthine schwannoma (ILS) is a rare benign tumor affecting cochlear and vestibular nerves, whose symptoms are generally unspecific and frequently responsible for a late diagnosis. Radiological examinations, with particular reference to magnetic resonance imaging (MRI), represent the only diagnostic technique to identify ILS. On computed tomography ILS can only be indirectly suspected by the presence of surrounding bone remodeling, whereas MRI provides direct visualization of the neoplasm as a filling defect within the labyrinth with vivid contrast enhancement. At the same time, MRI is also helpful in defining ILS anatomical extension into adjacent structures and in planning therapeutic management. Here we report three representative cases of ILS with new pictorial imaging features to improve ILS early detection and optimize subsequent therapeutic management.
迷路内神经鞘瘤（ILS）是一种罕见的良性肿瘤，累及耳蜗和前庭神经，其症状通常不具有特异性，常常导致诊断延迟。影像学检查，尤其是磁共振成像（MRI），是识别ILS的唯一诊断技术。在计算机断层扫描上，只能通过周围骨质重塑间接怀疑ILS，而MRI能直接将肿瘤显示为迷路内的充盈缺损，并伴有明显的对比增强。同时，MRI也有助于确定ILS向相邻结构的解剖学延伸，并规划治疗方案。在此，我们报告三例具有新影像学特征的ILS代表性病例，以提高ILS的早期检测并优化后续治疗方案。
