硼中子俘获疗法治疗透明细胞肉瘤。
Boron neutron capture therapy for clear cell sarcoma.
机构信息
Department of Orthopaedic Surgery, Hyogo Cancer Center, 13-70 Kitaouji-cho, Akashi, 673-8558, Japan; Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.
Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2 Asashiro-Nishi, Kumatori-cho, Sennan-gun, 590-0494, Japan.
出版信息
Appl Radiat Isot. 2020 Dec;166:109324. doi: 10.1016/j.apradiso.2020.109324. Epub 2020 Aug 3.
Clear cell sarcoma of tendons and aponeuroses (CCS) is a rare, malignant tumor arising in lower extremities with no effective treatment other than wide surgical resection. Here described is a case of primary CCS in the peroneal tendon of the right foot of a 54-year-old woman enrolled to undergo BNCT. The tumor mass post-BNCT disappeared totally without damage to other normal tissue, demonstrating, for the first time, the potential efficacy of BNCT in complete local control of CCS.
腱膜和腱旁组织透明细胞肉瘤（CCS）是一种罕见的恶性肿瘤，主要发生在下肢，除了广泛的手术切除外，没有其他有效的治疗方法。本文描述了一例 54 岁女性右足腓肠肌腱的原发性 CCS 病例，该患者接受 BNCT 治疗。BNCT 治疗后肿瘤完全消失，没有对其他正常组织造成损伤，首次证明了 BNCT 在完全控制 CCS 方面的潜在疗效。
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