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富血小板血浆对激光治疗藏毛窦疾病中切开引流术愈合的影响。

Effect of platelet-rich plasma on healing in laser pilonidoplasty for pilonidal sinus disease.

机构信息

Adana Seyhan State Hospital, Adana, Turkey.

Sözen Surgery Clinic, İstanbul, Turkey.

出版信息

Lasers Med Sci. 2021 Jul;36(5):1015-1021. doi: 10.1007/s10103-020-03137-5. Epub 2020 Aug 29.

DOI:10.1007/s10103-020-03137-5
PMID:32862404
Abstract

The aim of this study was to evaluate the effects of application of platelet-rich plasma in addition to laser pilonidoplasty for the treatment of pilonidal sinus. Twenty-five patients who were treated by laser pilonidoplasty for pilonidal sinus (group 1) and 25 patients who were treated by platelet-rich plasma in addition to laser pilonidoplasty (group 2) at this clinic were included in the study. Patients were classified according to the Irkorucu and Adana Numune's classification and treatment concept. Duration of stay of the patients in the hospital, time to start daily activities, duration of wound healing, recurrence, and complications were evaluated. Among the 50 patients included in the study, 41 (%82) were males and 9 (%18) were females. The mean age was 25.6 ± 2.4 years and 24.8 ± 3.8 years in groups 1 and 2, respectively. The locations of the pilonidal sinus were similar in the two groups. No statistically significant differences were found in the duration of hospital stay, duration of the procedure, time to return to work, and complication rates between the two groups. Nevertheless, duration of wound healing was 6.1 ± 2.3 and 4.1 ± 0.9 weeks in groups 1 and 2, respectively, and was shorter in group 2. Duration of wound healing was statistically significantly different in the two groups. We concluded in this study that application of platelet-rich plasma in addition to laser pilonidoplasty significantly shortens the time of wound healing.

摘要

本研究旨在评估在激光切开术治疗藏毛窦的基础上应用富血小板血浆(PRP)的效果。该诊所共纳入 25 例接受激光切开术治疗藏毛窦的患者(第 1 组)和 25 例接受激光切开术联合 PRP 治疗的患者(第 2 组)。患者根据 Irkorucu 和 Adana Numune 的分类和治疗概念进行分类。评估患者的住院时间、开始日常活动的时间、伤口愈合时间、复发率和并发症。在纳入的 50 例患者中,男性 41 例(82%),女性 9 例(18%)。第 1 组和第 2 组患者的平均年龄分别为 25.6±2.4 岁和 24.8±3.8 岁。两组患者的藏毛窦位置相似。两组患者的住院时间、手术时间、重返工作时间和并发症发生率无统计学差异。然而,第 1 组和第 2 组的伤口愈合时间分别为 6.1±2.3 周和 4.1±0.9 周,第 2 组的伤口愈合时间更短。两组之间的伤口愈合时间存在显著差异。本研究得出结论,在激光切开术治疗藏毛窦的基础上应用富血小板血浆可以显著缩短伤口愈合时间。

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引用本文的文献

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Platelet-rich plasma for pilonidal disease: a systematic review.富血小板血浆治疗藏毛窦病:系统评价。
J Int Med Res. 2023 Dec;51(12):3000605231216590. doi: 10.1177/03000605231216590.
2
Laser ablation: a unique and beneficial therapeutic option for pilonidal sinus? And the potential for further innovation-a review.激光消融:一种独特且有益的治疗肛旁窦的选择?以及进一步创新的潜力——综述。
Lasers Med Sci. 2023 May 18;38(1):124. doi: 10.1007/s10103-023-03788-0.
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Platelet-Rich Plasma (PRP) for Sacrococcygeal Pilonidal Disease: An Updated Systematic Review and Meta-Analysis.

本文引用的文献

1
Platelet-rich plasma: support for its use in wound healing.富血小板血浆:支持其在伤口愈合中的应用。
Yale J Biol Med. 2010 Mar;83(1):1-9.
2
[Treatment of pilonidal sinus].[藏毛窦的治疗]
Ugeskr Laeger. 2008 Sep 15;170(38):2963-8.
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Laser and light treatments for pilonidal cysts.
Cutis. 2006 Aug;78(2):125-8.
富血小板血浆(PRP)治疗骶尾部藏毛窦病:一项更新的系统评价和荟萃分析。
World J Surg. 2022 Dec;46(12):2910-2918. doi: 10.1007/s00268-022-06711-w. Epub 2022 Sep 5.