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新冠疫情期间儿童心肌受累模式:来自意大利北部的早期经验

Patterns of myocardial involvement in children during COVID-19 pandemic: Early experience from northern Italy.

作者信息

Ferrero Paolo, Piazza Isabelle, Bonino Caterina, Ciuffreda Matteo

机构信息

Department of Cardiology, ASST Papa Giovanni XXIII, Bergamo, Italy.

University of studies of Milan, Italy.

出版信息

Ann Pediatr Cardiol. 2020 Jul-Sep;13(3):230-233. doi: 10.4103/apc.APC_77_20. Epub 2020 Jul 7.

DOI:10.4103/apc.APC_77_20
PMID:32863659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7437629/
Abstract

There is limited information about coronavirus disease 2019 (COVID-19) in the pediatric population. Preliminary data suggest a not insignificant prevalence of cardiac involvement. Here, we report our early experience with COVID-19 in the pediatric population. These patients display exceptionally high levels of acute-phase reactants. The clinical syndrome in these patients is somewhat similar to Kawasaki disease with or without myocardial involvement. In some cases, the presentation mimics typical myocarditis. Severe myocardial involvement is associated with transient electrocardiographic and echocardiographic abnormalities. These findings may be due to the cardiotropic nature of the virus or may be the result of an immunologic response to the infection.

摘要

关于2019冠状病毒病(COVID-19)在儿科人群中的信息有限。初步数据表明心脏受累的患病率不容小觑。在此,我们报告我们在儿科人群中治疗COVID-19的早期经验。这些患者的急性期反应物水平异常高。这些患者的临床综合征在某种程度上类似于川崎病,伴或不伴有心肌受累。在某些情况下,其表现类似于典型心肌炎。严重心肌受累与短暂的心电图和超声心动图异常有关。这些发现可能是由于病毒的嗜心性,也可能是感染免疫反应的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be37/7437629/ef933f60ad31/APC-13-230-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be37/7437629/e159f3730a74/APC-13-230-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be37/7437629/ef933f60ad31/APC-13-230-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be37/7437629/e159f3730a74/APC-13-230-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be37/7437629/ef933f60ad31/APC-13-230-g002.jpg

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