Azimizadeh Mahdieh, Hosseini Seyedeh Maryam, Babaei Esmaeil
Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Retina Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
J Ophthalmic Vis Res. 2020 Aug 6;15(3):419-423. doi: 10.18502/jovr.v15i3.7461. eCollection 2020 Jul-Sep.
To report a case of choroidal osteoma associated with reactivation of choroidal neovascularization (CNV) and development of focal choroidal excavation (FCE).
A 34-year-old woman with choroidal osteoma complicated by CNV in the right eye for two years presented with deterioration of visual acuity in her right eye. A small retinal hemorrhage accompanied by subretinal fluid (SRF) was seen in the macular area of the right eye. Optical coherence tomography (OCT) showed that the inner retina was intact, and the outer retinal layers had outward displacement. SRF and a wedge-shaped choroidal depression were also seen. This choroidal excavation was not present on previous OCT images. The integrity of the inner retinal layers was maintained, and an optically clear space was present between the neurosensory retina and the retinal pigment epithelium.
Choroidal osteoma can be complicated by CNV and FCE could occur as a consequence. Again, FCE can lead to CNV development. This cascade can deteriorate vision and sometime lead to permanent visual loss.
报告一例脉络膜骨瘤合并脉络膜新生血管(CNV)再激活及局灶性脉络膜凹陷(FCE)形成的病例。
一名34岁女性,右眼脉络膜骨瘤合并CNV两年,右眼视力下降。右眼黄斑区可见少量视网膜出血伴视网膜下液(SRF)。光学相干断层扫描(OCT)显示内层视网膜完整,外层视网膜层向外移位。还可见SRF和楔形脉络膜凹陷。之前的OCT图像上未见这种脉络膜凹陷。内层视网膜层保持完整,神经感觉视网膜与视网膜色素上皮之间存在一个光学透明间隙。
脉络膜骨瘤可合并CNV,进而可能导致FCE。此外,FCE可导致CNV形成。这种级联反应可使视力恶化,有时会导致永久性视力丧失。