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简短通讯：麻疹疫苗与10价肺炎球菌结合疫苗同时接种时的免疫原性

Brief communication: immunogenicity of measles vaccine when co-administered with 10-valent pneumococcal conjugate vaccine.

作者信息

Toh Zheng Quan, Temple Beth, Huu Tran Ngoc, Dai Vo Thi Trang, Toan Nguyen Trong, Uyen Doan Y, Bright Kathryn, Do Lien Anh Ha, Mulholland E Kim, Licciardi Paul V

机构信息

New Vaccines, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC Australia.

Department of Paediatrics, The University of Melbourne, Parkville, VIC Australia.

出版信息

NPJ Vaccines. 2020 Aug 18;5:76. doi: 10.1038/s41541-020-00225-z. eCollection 2020.

DOI:10.1038/s41541-020-00225-z
PMID:32864166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7434759/
Abstract

This brief communication describes the findings from a randomised controlled trial in Vietnam that co-administration of measles vaccine (MV) with 10-valent pneumococcal conjugate vaccine (PCV10, Synflorix®, GSK) does not affect the immunogenicity of MV. These findings are most relevant for low- and middle-income countries (LMICs) in Asia considering PCV introduction.

摘要

这篇简短通讯描述了越南一项随机对照试验的结果，即麻疹疫苗（MV）与10价肺炎球菌结合疫苗（PCV10，Synflorix®，葛兰素史克公司）联合接种不影响MV的免疫原性。考虑引入PCV的情况下，这些发现对亚洲的低收入和中等收入国家（LMICs）最为重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0f/7434759/07b55c206b76/41541_2020_225_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0f/7434759/07b55c206b76/41541_2020_225_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e0f/7434759/07b55c206b76/41541_2020_225_Fig1_HTML.jpg

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Immunogenicity of pneumococcal conjugate vaccine formulations containing pneumococcal proteins, and immunogenicity and reactogenicity of co-administered routine vaccines - A phase II, randomised, observer-blind study in Gambian infants.含肺炎球菌蛋白的肺炎球菌结合疫苗制剂的免疫原性，以及同时接种常规疫苗的免疫原性和反应原性 - 冈比亚婴儿的 II 期、随机、观察者盲法研究。
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Evaluation of different infant vaccination schedules incorporating pneumococcal vaccination (The Vietnam Pneumococcal Project): protocol of a randomised controlled trial.纳入肺炎球菌疫苗接种的不同婴儿疫苗接种计划评估（越南肺炎球菌项目）：一项随机对照试验方案
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Vaccine. 2019 Jan 7;37(2):219-222. doi: 10.1016/j.vaccine.2017.07.066. Epub 2017 Jul 29.
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Hepatitis B vaccines: WHO position paper, July 2017 - Recommendations.乙型肝炎疫苗：世卫组织立场文件，2017 年 7 月-建议。
Vaccine. 2019 Jan 7;37(2):223-225. doi: 10.1016/j.vaccine.2017.07.046. Epub 2017 Jul 22.
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