World Health Organization, Immunization, Vaccines and Biologicals, 20 Ave Appia, CH-1211 Geneva 27, Switzerland.
Vaccine. 2019 Jan 7;37(2):223-225. doi: 10.1016/j.vaccine.2017.07.046. Epub 2017 Jul 22.
This article presents the World Health Organization's (WHO) recommendations on the use of hepatitis B vaccines excerpted from the Hepatitis B vaccines: WHO position paper, July 2017, published in the Weekly Epidemiological Record (Hepatitis B vaccines, 2017) [1]. This position paper replaces the May 2009 WHO position paper on hepatitis B vaccines (Hepatitis B vaccines, 2009) [2]. The position paper gives updated information on hepatitis B vaccines and their storage, transport and deployment. The recommendations concern the target groups for vaccination and the appropriate schedules. In particular, the recommendations stress the importance of vaccination of all infants at birth as the most effective intervention for the prevention of hepatitis B virus-associated disease worldwide. Footnotes to this paper provide a number of core references including references to grading tables that assess the quality of the scientific evidence, and to the evidence-to-recommendation table. In accordance with its mandate to provide guidance to Member States on health policy matters, WHO issues a series of regularly updated position papers on vaccines and combinations of vaccines against diseases that have an international public health impact. These papers are concerned primarily with the use of vaccines in large-scale immunization programmes; they summarize essential background information on diseases and vaccines, and conclude with WHO's current position on the use of vaccines in the global context. Recommendations on the use of hepatitis B vaccines were discussed by SAGE in October 2016; evidence presented at these meetings can be accessed at: http://www.who.int/immunization/sage/meetings/2016/October/presentations_background_docs/en/.
本文摘录自 2017 年 7 月《世界卫生组织乙型肝炎疫苗立场文件》（《每周流行病学记录》，乙型肝炎疫苗，2017 年）[1]，介绍了世界卫生组织（世卫组织）关于乙型肝炎疫苗使用的建议。本立场文件取代了 2009 年 5 月《世卫组织乙型肝炎疫苗立场文件》（乙型肝炎疫苗，2009 年）[2]。该立场文件提供了乙型肝炎疫苗及其储存、运输和使用的最新信息。建议涉及疫苗接种的目标人群和适当的时间表。特别是，建议强调了在全球范围内为所有婴儿出生时接种疫苗作为预防乙型肝炎病毒相关疾病的最有效干预措施的重要性。本文脚注提供了一些核心参考资料，包括评估科学证据质量的分级表和证据推荐表的参考资料。根据其向会员国提供卫生政策事项指导的任务规定，世卫组织定期发布关于对具有国际公共卫生影响的疾病的疫苗和疫苗组合的立场文件。这些文件主要涉及大规模免疫规划中疫苗的使用；它们概括了有关疾病和疫苗的必要背景信息，并总结了世卫组织在全球范围内使用疫苗的当前立场。乙型肝炎疫苗使用建议已于 2016 年 10 月由免疫战略咨询专家组（SAGE）讨论；这些会议上提交的证据可在以下网址获取：http://www.who.int/immunization/sage/meetings/2016/October/presentations_background_docs/en/。
