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Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy.意大利米兰一家学术医院收治的 COVID-19 患者的静脉和动脉血栓栓塞并发症。
Thromb Res. 2020 Jul;191:9-14. doi: 10.1016/j.thromres.2020.04.024. Epub 2020 Apr 23.
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N Engl J Med. 2020 May 14;382(20):e60. doi: 10.1056/NEJMc2009787. Epub 2020 Apr 28.
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Concomitant acute aortic thrombosis and pulmonary embolism complicating COVID-19 pneumonia.新型冠状病毒肺炎并发急性主动脉血栓形成和肺栓塞
Diagn Interv Imaging. 2020 May;101(5):321-322. doi: 10.1016/j.diii.2020.04.003. Epub 2020 Apr 16.
4
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J Thromb Haemost. 2020 Aug;18(8):2064-2065. doi: 10.1111/jth.14867. Epub 2020 May 11.
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Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands.新型冠状病毒肺炎相关血栓栓塞性并发症的诊断、预防和治疗:荷兰国家公共卫生研究所报告。
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Incidence of thrombotic complications in critically ill ICU patients with COVID-19.COVID-19 重症监护病房危重症患者的血栓并发症发生率。
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Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19.新型冠状病毒肺炎患者的凝血障碍与抗磷脂抗体
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Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy.抗凝治疗与伴有凝血功能障碍的严重 2019 冠状病毒病患者的死亡率降低相关。
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急性肢体缺血作为新型冠状病毒2型感染的唯一初始表现。

Acute limb ischemia as sole initial manifestation of SARS-CoV-2 infection.

作者信息

Thompson Owen, Pierce Damon, Whang Dennis, O'Malley Meaghan, Geise Bob, Malhotra Uma

机构信息

Department of Medicine, Virginia Mason Medical Center, Seattle, Wash.

Department of Vascular Surgery, Virginia Mason Medical Center, Seattle, Wash.

出版信息

J Vasc Surg Cases Innov Tech. 2020 Dec;6(4):511-513. doi: 10.1016/j.jvscit.2020.07.017. Epub 2020 Aug 21.

DOI:10.1016/j.jvscit.2020.07.017
PMID:32864520
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7441972/
Abstract

We present the case of a patient with acute upper limb ischemia as the sole initial manifestation of severe acute respiratory syndrome associated with coronavirus disease 2 infection, without concomitant respiratory symptoms or pneumonia. Viral infection presumably precipitated the patient's thromboembolic event, causing multifocal vascular occlusions. This case illustrates that coronavirus disease-19 must be considered in the differential diagnosis of patients presenting with signs or symptoms of coagulopathy, even in the absence of respiratory symptoms. We believe that an awareness of the variety of clinical presentations in patients with coronavirus disease-19, particularly extrapulmonary manifestations, is critical for optimal patient management as well as implementation of appropriate infection prevention measures.

摘要

我们报告了一例患者,其急性上肢缺血是新型冠状病毒2型感染所致严重急性呼吸综合征的唯一初始表现,且无伴随的呼吸道症状或肺炎。病毒感染可能引发了患者的血栓栓塞事件,导致多灶性血管闭塞。该病例表明,即使没有呼吸道症状,对于出现凝血功能障碍体征或症状的患者进行鉴别诊断时也必须考虑新型冠状病毒肺炎。我们认为,了解新型冠状病毒肺炎患者的各种临床表现,尤其是肺外表现,对于优化患者管理以及实施适当的感染预防措施至关重要。