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瑞德西韦与肺部药物的潜在相互作用:从新冠肺炎角度看

Potential Interactions of Remdesivir with Pulmonary Drugs: a Covid-19 Perspective.

作者信息

Gandhi Zainab, Mansuri Zeeshan, Bansod Snehal

机构信息

Department of Infectious Diseases, University of California, San Francisco, CA USA.

Department of Psychiatry, Texas Tech University Health Science Center at Odessa/Permian Basin, Odessa, TX USA.

出版信息

SN Compr Clin Med. 2020;2(10):1707-1708. doi: 10.1007/s42399-020-00462-2. Epub 2020 Aug 21.

DOI:10.1007/s42399-020-00462-2
PMID:32864571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7441835/
Abstract

In this letter, we discuss the potential interactions of remdesivir, the newly approved Covid-19 drug with pulmonary medications. These interactions have been summarized keeping the busy clinician in mind. While remdesivir has proven to be a safe medication generally, we here have enlisted the potential interactions of remdesivir that a clinician needs to be mindful of while prescribing the medication.

摘要

在这封信中,我们讨论了新获批的治疗新冠病毒病药物瑞德西韦与肺部用药之间可能存在的相互作用。总结这些相互作用时,我们考虑到了忙碌的临床医生的需求。虽然瑞德西韦总体上已被证明是一种安全的药物,但我们在此列出了临床医生在开具该药物处方时需要留意的瑞德西韦的潜在相互作用。

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本文引用的文献

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Remdesivir in COVID-19: A critical review of pharmacology, pre-clinical and clinical studies.瑞德西韦治疗新型冠状病毒肺炎:药理学、临床前及临床研究的批判性综述
Diabetes Metab Syndr. 2020 Jul-Aug;14(4):641-648. doi: 10.1016/j.dsx.2020.05.018. Epub 2020 May 12.
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A Precision Medicine Approach to SARS-CoV-2 Pandemic Management.一种用于新冠病毒大流行管理的精准医学方法。
Curr Treat Options Allergy. 2020;7(3):422-440. doi: 10.1007/s40521-020-00258-8. Epub 2020 May 8.
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Coronavirus Disease 2019 Treatment: A Review of Early and Emerging Options.2019年冠状病毒病的治疗:早期及新出现的治疗选择综述
Open Forum Infect Dis. 2020 Mar 23;7(4):ofaa105. doi: 10.1093/ofid/ofaa105. eCollection 2020 Apr.
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Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir.瑞德西韦抑制埃博拉病毒 RNA 依赖的 RNA 聚合酶的机制。
Viruses. 2019 Apr 4;11(4):326. doi: 10.3390/v11040326.
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Clinical Applications of Personalized Medicine: A New Paradigm and Challenge.个性化医疗的临床应用:一种新范式与挑战。
Curr Pharm Biotechnol. 2017;18(3):194-203. doi: 10.2174/1389201018666170224105600.
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Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4.药物可作为人细胞色素P450 3A4的底物、抑制剂和诱导剂。
Curr Drug Metab. 2008 May;9(4):310-22. doi: 10.2174/138920008784220664.