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[各种病原体引起的感染性腹泻的特征与多样性]

[Characteristics and diversity of infectious diarrheal caused by various pathogens].

作者信息

He Z K, Wang J, Sun H, Su J, Liu X, Gu W P, Yu D S, Luo L Z, Wang M L, Hu B, Hu W F, Tong J, Yang M, Wang S L, Wang C X, Wang Y L, Zhan Z F, Duan R, Qin S, Jing H Q, Wang X

机构信息

National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.

Dongcheng District Center for Disease Control and Prevention, Beijing 100009, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Aug 10;41(8):1328-1334. doi: 10.3760/cma.j.cn112338-20200213-00093.

Abstract

To understand the characteristics and differences of diarrhea-related symptoms caused by different pathogens, and the clinical features of various pathogens causing diarrhea. Etiology surveillance program was conducted among 20 provinces of China from 2010 to 2016. The acute diarrhea outpatients were collected from clinics or hospitals. A questionnaire was used to survey demographics and clinical features. VFeces samples were taken for laboratory detection of 22 common diarrhea pathogens, to detect and analyze the clinical symptom pattern characteristics of the patient's. A total of 38 950 outpatients were enrolled from 20 provinces of China. The positive rates of Rotavirus and Norovirus were the highest among the five diarrhea-causing viruses (Rotavirus: 18.29%, Norovirus: 13.06%). In the isolation and culture of 17 diarrhea-causing bacterial, showed the highest positive rates (6.25%). The clinical features of bacterial diarrhea and viral diarrhea were mainly reflected in the results of fecal traits and routine examination, but pathogenic Vibrio infection was similar to viral diarrhea. Infectious diarrhea presents different characteristics due to various symptoms which can provide a basis for clinical diagnosis.

摘要

为了解不同病原体引起的腹泻相关症状的特点与差异,以及各类致泻病原体的临床特征。2010年至2016年在中国20个省份开展了病因监测项目。从诊所或医院收集急性腹泻门诊患者。采用问卷对人口统计学和临床特征进行调查。采集粪便样本用于22种常见腹泻病原体的实验室检测,以检测和分析患者的临床症状模式特征。共纳入中国20个省份的38950例门诊患者。在五种致泻病毒中,轮状病毒和诺如病毒的阳性率最高(轮状病毒:18.29%,诺如病毒:13.06%)。在17种致泻细菌的分离培养中,[细菌名称未给出]显示出最高的阳性率(6.25%)。细菌性腹泻和病毒性腹泻的临床特征主要体现在粪便性状和常规检查结果上,但致病性弧菌感染与病毒性腹泻相似。感染性腹泻因各种症状呈现出不同特点,可为临床诊断提供依据。

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