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通过全息飞秒多焦点光束制备的用于原位捕获微粒的自组装微柱。

Self-assembled micropillars fabricated by holographic femtosecond multi-foci beams forin situ trapping of microparticles.

作者信息

Hu Yanlei, Feng Wenfei, Xue Cheng, Lao Zhaoxin, Ji Shengyun, Cai Ze, Zhu Wulin, Li Jiawen, Wu Dong, Chu Jiaru

出版信息

Opt Lett. 2020 Sep 1;45(17):4698-4701. doi: 10.1364/OL.398682.

Abstract

Dynamic self-assembly of micropillars has found wide applications in targeted trapping, micro-crystallization and plasmonic sensing. Yet the efficient fabrication of micropillars array with high flexibility still remains a grand challenge. In this Letter, holographic femtosecond laser multi-foci beams (fs-MFBs) based on a spatial light modulator (SLM) is adopted to efficiently create micropillars array with controllable geometry and spatial distribution by predesigning the computer-generated holograms (CGHs). Based on these micropillars array, diverse hierarchical assemblies are formed under the evaporation-induced capillary force. Moreover, taking advantage of the excellent flexibility and controllability of fs-MFBs, on-demand one-bead-to-one-trap of targeted microspheres at arbitrary position is demonstrated with unprecedentedly high capture efficiency, unfolding their potential applications in the fields of microfluidics and biomedical engineering.

摘要

微柱的动态自组装已在靶向捕获、微晶化和等离子体传感等领域得到广泛应用。然而,高效制备具有高灵活性的微柱阵列仍然是一个巨大的挑战。在本文中,基于空间光调制器(SLM)的全息飞秒激光多焦点光束(fs-MFBs)被用于通过预先设计计算机生成全息图(CGHs)来高效创建具有可控几何形状和空间分布的微柱阵列。基于这些微柱阵列,在蒸发诱导的毛细力作用下形成了多种层次结构的组装体。此外,利用fs-MFBs优异的灵活性和可控性,以前所未有的高捕获效率展示了在任意位置按需对目标微球进行单珠单捕,展现了它们在微流控和生物医学工程领域的潜在应用。

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